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Anti-Infectives
Levofloxacin prevents bacterial infection in patients with cancer and neutropenia
October 25th, 2005
Prophylactic use of levofloxacin can prevent bacterial infection in patients with cancer and neutropenia. "The prophylactic use of fluoroquinolones in patients with cancer and neutropenia is controversial and is not a recommended intervention. We randomly assigned 760 consecutive adult patients with cancer in whom chemotherapy-induced neutropenia (<1000 neutrophils per cubic millimeter) was expected to occur for more than 7 days to receive either oral levofloxacin (500 mg daily) or placebo from the start of chemotherapy until the resolution of neutropenia," scientists writing in the New England Journal of Medicine reported. "Patients were...
Source: cancer weekly (2005-10-25)
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