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Apoptosis



Microarray analysis identifies apoptosis gene in V. parahaemolyticus infected cells



October 25th, 2005

Microarray analysis identifies apoptosis regulatory gene expression in HCT116 cells infected with thermostable direct hemolysin-deletion mutant of Vibrio parahaemolyticus.

According to recent research from Japan, "The thermostable direct hemolysin (TDH) is considered as a major virulence factor of Vibrio parahaemolyticus. We observed this potential in several human cancer cell lines by using the TDH-producing wild-type (RIMD2210633) as well as tdh-deletion mutant of V. parahaemolyticus and found that the deletion of tdh did not affect cytotoxicity to any of the cell lines tested."

"DNA fragmentation and annexin V staining showed...


Source: cancer weekly (2005-10-25)

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