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Apoptosis
Researchers' data advance apoptosis research
October 25th, 2005
Data on apoptosis are outlined in reports from Japan and the United States. Study 1: 53BP2S-mediated apoptosis could be inhibited by nuclear factor kappa B (NF-kappa B) and Bcl-2 proteins. According to recent research from Japan, "The p53 binding protein 2 (53BP2) has been identified independently as the interacting protein to p53, Bcl-2, and p65 subunit of NF-kappa B. It was demonstrated that over-expression of 53BP2 (renamed as 53BP2S) induces apoptotic cell death." "In this study we explored the effect of NF-kappa B activation elicited by a physiological NF-kappa B inducer, interleukin-1 beta (IL-1 beta), and anti-apoptotic...
Source: cancer weekly (2005-10-25)
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