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Cancer Vaccines
Researchers' work adds to cancer vaccines body of knowledge
October 25th, 2005
Cancer vaccines data are the focus of recent research from the United Kingdom, Australia and United States. Study 1: Scientists report the results of a phase 1 study of TNF-alpha AutoVaccIne in patients with metastatic cancer in a recent issue of Cancer Immunology, Immunotherapy. "We evaluated the safety and immunogencity of a novel vaccine directed against autologous TNF-alpha in a phase I fixed-dose escalation trial. The vaccine consisted of two recombinant TNF-alpha proteins, with specific peptides replaced by foreign immunodominant T cell epitopes from tetanus toxoid. The main objectives were to establish a safe dose and evaluate the...
Source: cancer weekly (2005-10-25)
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