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Cancer Detection



Factors accounting for decline in PIN predictive values described



October 25th, 2005

Factors that might account for the decline in prostatic intraepithelial neoplasia (PIN) predictive values were described.

"In earlier studies, prostate cancer (PCa) has been reported to appear in 21% to 48% of subsequent biopsies for isolated high-grade PIN and in 34% to 60% for isolated atypical small acinar proliferation suspicious for, but not diagnostic of, malignancy (ASAP). We report results of follow-up biopsies in a recent cohort of community practice patients who underwent biopsy for PSA abnormalities," scientists reported in the American Journal of Surgical Pathology.

"The study group consisted of 336 men with initial diagnoses of...


Source: cancer weekly (2005-10-25)

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