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Alcohol Use
Alcohol consumption implicated in carcinogenesis
October 25th, 2005
Alcohol consumption might impair folate metabolism and increase the risk of cancer. "Epidemiologic observations implicate excess ethanol ingestion as well as low dietary folate intake as risk factors for several cancers. Moreover, the epidemiologic observations support the concept of a synergistic effect between these two factors," scientists in the United States reported. "Such a relation is biologically plausible because ethanol impedes the bioavailability of dietary folate and is known to inhibit select folate-dependent biochemical reactions. For example, alcohol ingestion in animals is known to inhibit folate-mediated methionine synthesis and...
Source: cancer weekly (2005-10-25)
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