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Bulgarian Academy of Sciences
Reproductive death delayed in progeny of irradiated melanoma cells
June 23rd, 2004
Researchers have investigated delayed reproductive death and reactive oxygen species (ROS) levels in the progeny of irradiated melanoma cells. "The cell death and survival of proliferating (clonogenic) cells were investigated in two human melanoma cell lines to assess the optimal conditions for preparation of apoptotic bodies from melanoma cells. After 50 J/m2 UVB+UVC the maximal levels of apoptotic cells assayed by Trypan blue staining, nucleosomal DNA fragmentation, MTT, and TUNEL tests were observed within 2 to 3 days of radiation. In 100 Gy gamma-irradiated cultures these apoptosis indicators were delayed for up to 3 weeks," scientists writing in the...
Source: elder law weekly (2004-06-23)
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