Hospital de Especialidades del Centro Medico Nacional Siglo XXI, Mexico City
Salmonella porins induce lifelong specific bactericidal antibody memory
Published in medicine and law weekly, March 24th, 2006
According to recent research published in the journal Immunology, "We examined the ability of porins from Salmonella enterica serovar typhi to induce a long-term antibody response in BALB/c mice. These porins triggered a strong lifelong production of immunoglobulin G (IgG) antibody in the absence of exogenous adjuvant. Analysis of the IgG subclasses produced during this antibody response revealed the presence of the subclasses IgG2b, IgG1, IgG2a, and weak IgG3."
"Despite the high homology of porins, the long-lasting anti-S. typhi porin...
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