Depression, anxiety disorders and sexual trauma have all been implicated as risk factors in lower urinary tract symptoms (LUTS) such as incontinence and overactive bladder. The exact nature of these associations is unknown. In a study published online in The Journal of Urology, researchers from the Division of Urology, Virginia Commonwealth University School of Medicine and the Hunter Holmes McGuire Veterans Affairs Hospital, Richmond, Virginia, explored the possible association of LUTS with those factors.
Two questionnaires, the Urogenital Distress Inventory-6 and Incontinence Impact Questionnaire-7, were administered to 121 women referred to a specialized urology clinic for evaluation of lower urinary tract symptoms. These data were then analyzed according to psychiatric comorbidities, history of sexual trauma, age, race and obstetric history. Baseline incidence of psychiatric comorbidity and sexual trauma was also compared to a control population of 1,298 women from the Veterans Affairs primary care clinic.
Women referred for evaluation of lower urinary tract symptoms had higher rates of psychiatric comorbidities (64.5% vs. 25.9%) and sexual trauma (49.6% vs. 20.1%) compared to those in the primary care clinic. Separate analysis showed that women younger than 50 years and with a history of miscarriage had higher Urogenital Distress Inventory-6 scores, while higher Incontinence Impact Questionnaire-7 scores were associated only with psychiatric comorbidities and history of miscarriage.
Writing in the article, Adam P. Klausner, MD, and colleagues state, “This is the first study to our knowledge to characterize the association of psychiatric comorbidities and sexual trauma with the type, severity and quality of life impact of LUTS in women using validated surveys. The prevalence of psychiatric comorbidities and sexual trauma is high in women veterans presenting for evaluation of LUTS.” Dr. Klausner is an associate professor and the Director of Neurourology, Female Urology, and Voiding Dysfunction at Virginia Commonwealth University Medical Center.
The article is “The Influence of Psychiatric Comorbidities and Sexual Trauma on Lower Urinary Tract Symptoms in Women Veterans” by Adam P. Klausner, Diane Ibanez, Ashley B. King, Daniel Willis, Benjamin Herrick, Luke Wolfe and B. Mayer Grob. It is published online (DOI:10.1016/j.juro.2009.08.035) and will appear in The Journal of Urology, Volume 182, Issue 6 (December 2009) published by Elsevier.
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Full text of the article featured above is available upon request. Contact Linda Gruner at 212-633-3923 or email jumedia@elsevier.com to obtain a copy. To schedule an interview with Dr. Klausner please contact Sathya Achia Abraham, Office of Communications and Public Relations, Virginia Commonwealth University at 804-827-0890 or email sbachia@vcu.edu.
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Established in 1917, The Journal of Urology (www.jurology.com) is the official journal of the American Urological Association (www.auanet.org). It is the most widely read and highly cited journal in the field. It brings to its readership all the clinically relevant information needed to stay at the forefront of this dynamic field. This top-ranking journal presents investigative studies on critical areas of research and practice, survey articles providing short condensations of the best and most important urology literature worldwide and practice-oriented reports on interesting clinical observations.
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