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2009 SEP 28 ... this work investigated whether this effect involves the regulation of adipogenesis. 3T3-L1 preadipocytes were induced to differentiate in the absence or presence of melatonin ... Scientists discuss in 'Adipocyte differentiation is inhibited by melatonin through the regulation of C/EBPbeta ...
2009 NOV 9 ... technology dramatically increased growth rate and impaired adipocyte differentiation in 3T3-L1 cells. Furthermore, we showed that HMGA1 strongly potentiates the capacity of the ...
2009 NOV 1 ... "We found that menin is required for adipocyte differentiation of murine 3T3-L1 cells and PPAR gamma-expressing mouse embryonic fibroblasts. Menin augments PPAR gamma ...
2009 OCT 19 ... in both in vitro differentiated human primary adipocytes and differentiated murine 3T3-L1 cells. Moreover, activation of LXR causes PDK4-dependent phosphorylation of the pyruvate ... characterized. Increased adipose tissue mass in obesity is associated with increased adipocyte lipolysis." "Fatty acids (FA) generated by lipolysis can be oxidized by ...
2009 NOV 23 ... adipogenesis-inducing medium induces MCP-1 production and expression of MCPIP in 3T3-L1 cells before the induction of the C/EBP family of transcription factors and PPAR gamma. ... of MCPIP prevents their expression and adipogenesis as measured by expression of adipocyte markers and lipid droplet accumulation. Treatment of 3T3-L1 cells with MCP-1 or forced ...
2009 NOV 1 ... Obese ob/ob and db/db mice were treated with eplerenone, a MR antagonist, for 3 weeks. 3T3-L1 adipocytes were treated with aldosterone or H2O2, with and without eplerenone or ... whether MR blockade attenuates obesity-related insulin resistance and improves adipocyte dysfunction. Obese ob/ob and db/db mice were treated with eplerenone, a MR antagonist, ...
2009 SEP 21 ... inducers on resistin mRNA and secreted protein levels were examined in differentiated 3T3-L1 adipocytes, focusing on the expression and genomic binding of transcriptional regulators ... and colleagues published their study in Diabetes (Endoplasmic Reticulum Stress Regulates Adipocyte Resistin Expression. Diabetes, 2009;58(8):1879-1886). For more information, ...
2009 NOV 16 ... "Bscl2 mRNA is highly up-regulated during standard hormone-induced adipogenesis in 3T3-L1 cells in vitro. However, this up-regulation does not occur during mesenchymal stem cell ... largely unknown. In this study, we investigated the role of Bscl2 in the regulation of adipocyte differentiation." "Bscl2 mRNA is highly up-regulated during standard ...
2009 NOV 11 ... acts as a Ca2+-dependent molecular switch that negatively regulates the ability of 3T3-L1 cells to undergo adipocyte differentiation by preventing the expression of critical ...
2009 SEP 21 ... ablation on adipocyte function. To this end, we obtained several multiclonal mouse 3T3-L1 cell lines with a reduced expression of caveolin-1 (95% reduction) by a small ...
2009 NOV 26 ... eight-and 10-carbon medium-chain fatty acids (MCFAs), on apoptotic signaling in 3T3-L1 adipocytes was investigated. 3T3-L1 adipocytes were treated with various concentrations ... of anti-apoptotic Bcl-2. These results show that octanoate and decanoate mediate adipocyte apoptosis via a caspase-dependent mitochondrial pathway in 3T3-L1 adipocytes," wrote ...
2009 SEP 22 ... According to a study from Shanghai, People's Republic of China, "The first stage of 3T3-L1 adipocyte differentiation is growth arrest, which is achieved by contact inhibition at confluence. ...
2009 NOV 30 ... to identify and quantify secretory factors that are differentially secreted by 3T3-L1 adipocytes with or without insulin treatment. Combination of cICAT and label-free ... is now available. According to a study from Shanghai, People's Republic of China, "Adipocyte is not only a central player involved in storage and release of energy, but also in ...
2009 OCT 5 ... zymosan A (ZymA), induced insulin resistance in a time- and dose-dependent manner in 3T3-L1 adipocytes. Corresponding with the reduction of insulin sensitivity was an increased ... reduced ROS accumulation. Collectively, these results demonstrated Tlr2 involvement in adipocyte inflammation and therefore implicated the receptor as a potential target for SFA," ...
2009 NOV 30 ... balance mainly through feeding modulation. In addition, AEA has been found to increase 3T3-L1 adipocyte differentiation process." "In this study, the effect of AEA, ...
2009 NOV 30 ... inflammation-related changes in gene or/and protein expressions of several adipokines in 3T3-L1 adipocytes and of LPS-induced inflammatory factors in RAW 264.7 cell," scientists in ... their study in Inflammation (Salicylate Inhibits Macrophage-Secreted Factors Induced Adipocyte Inflammation and Changes of Adipokines in 3T3-L1 Adipocytes. Inflammation, ...
2009 NOV 9 ... using yeast two-hybrid assay, Gal4/UAS cell-based assay and SPR based assay. The 3T3-L1 cell differentiation assay was used to evaluate the effect of the active compound on ... a natural product library for novel PPAR gamma antagonists with inhibitory effects on adipocyte differentiation." "Surface plasmon resonance (SPR) technology and ...
