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2009 NOV 9 ... seeking to develop small molecule activators of AMP activated protein kinase. Novel AMPK activators hold promise for the treatment of type 2 diabetes, cardiovascular disease, ...
2009 NOV 23 ... According to a study from Zurich, Switzerland, "AMP-activated protein kinase (AMPK) is a heterotrimeric complex playing a crucial role in maintaining cellular energy ...
2009 NOV 16 ... by the regulation of the activity of HMGCoA reductase mediated by AMP-dependent kinase AMPK. We have compared the effect of octacosadienol and policosanol on the regulation of ...
2009 NOV 26 ... glucose in C2C12 myotubes, which was associated with both AMP-activated protein kinase (AMPK) and phosphatidylinositol 3-kinase (PI3-K) signaling pathways, but both of these ...
2009 NOV 23 ... these pathogenic processes." "Activation of AMP-activated protein kinase (AMPK) has been reported to reduce intraceRular reactive oxygen species (ROS) levels. The ...
2009 NOV 16 ... "We know a great deal about the cellular response to starvation via AMPK, but less is known about the reaction to nutrient excess. Insulin resistance may be an ...
2009 NOV 16 ... show that the reduced ATP levels lead to activation of 5'AMP-activated protein kinase (AMPK) and its downstream effector, c-Jun N-terminal kinase; thus, the increased sensitivity ...
2009 NOV 9 ... sterol-regulatory element-binding protein (SREBP)-1 and AMP-activated protein kinase (AMPK) in the mouse brain. Levels of these proteins including phosphorylated forms of ACC and ...
2009 NOV 16 ... effects of EGCG and Rutin through activating AMP-activated protein kinase (AMPK) signaling to inhibit the activities of lipogenic enzymes and ameliorating mitochondrial ...
2009 NOV 16 ... mitochondria. We have shown previously that activation of AMP-activated protein kinase (AMPK) protects hepatocytes from AA + iron-induced apoptosis." "Resveratrol, a ...
2009 NOV 23 ... which is well known as an activator of adenosine monophosphate-activated protein kinase (AMPK), was used. Metformin and AICAR enhanced phosphorylated...
2009 NOV 16 ... ECs and its expression in the mouse aorta is regulated by AMP-activated protein kinase (AMPK)," investigators in the United States report. ...
2009 NOV 10 ... that the nutrient-responsive adenosine monophosphate-activated protein kinase (AMPK) phosphorylates and destabilizes the clock component cryptochrome 1 (CRY1). In mouse ...
2009 NOV 25 ... via its HNF-4 alpha response element, and indirectly by lack of inhibitory crosstalk of AMPK, CAR and PXR with HNF-4 alpha," wrote V. Tamasi and colleagues, Semmelweis University, ...
2009 NOV 9 ... report. "Recent studies indicate that AMP-activated protein kinase (AMPK) plays a role in the cellular response to environmental stresses, which deplete ATP, and ...
2009 NOV 23 ... was applied to reveal the intracellular location of AMP-activated protein kinase (AMPK) subunits in liver tissue of normal rats fed ad libitum....
2009 NOV 9 ... According to a study from Scotland, "AMP-activated protein kinase (AMPK) acts as a cellular fuel gauge that responds to energy stress by suppressing cell growth ...
