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2009 NOV 2 ... and colleagues published their study in Fundamental & Clinical Pharmacology (Effects of AT1 receptor and beta1 receptor blocking on blood pressure, peripheral hemodynamic and lipid profile ...
2009 JUL 27 ... under conditions of static stretch by 21%. The differential effects of selective AT1 receptor blockade by losartan, Cn blockade by Cyclosporine-A (CsA) or NFAT inhibition by ...
2009 NOV 16 ... dermal fibrosis. Our results show that Ang II activation of Smad2 occurs via the AT1 receptor, but not the AT2 receptor," wrote G.Y. Zhang and colleagues, Wenzhou Medical College. ...
2009 AUG 10 ... of the cells with rosiglitazone had little effect on Ang II receptors expression (AT1 and AT2), but downregulated AT1-dependent ERK1/2 activation. Then, treatment of VSMCs ... so as to promote the pathogenesis of atherosclerosis." "Toll-like receptor 4 (TLR4) activates signaling pathways leading to the expression of pro-inflammatory ...
2009 OCT 5 ... Research findings, 'In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat ...
2009 SEP 7 ... = 9) was compared by Western blotting to that of 2K1C rats treated with low doses of the AT1 antagonist losartan (10 mg. kg(-1). day(-1); N = 5) or the superoxide scavenger tempol ... of NO function." "We tested the hypothesis that the angiotensin II AT(1) receptor and oxidative stress mediated by NADPH oxidase contribute to the modulation of renal ...
2009 AUG 3 ... microinjection of different doses of IL-1 beta, IL-1 beta together with Losartan, an AT1 receptor antagonist, or Ang II pre-treated with IL-1 beta into PVN. Rats microinjected with ...
2009 AUG 24 ... "Long-Evans rats, C57BL/6 mice, and angiotensin II type 1 receptor (AT1-R)deficient mice with streptozotocin-induced diabetes were treated with (pro)renin ...
2009 AUG 10 ... (-P) SHR and WKY were used to compare the changes of angiotensin II (ANG II) type 1 (AT1) and type 2 (AT2) receptor expression in the kidney. Renal modification of ...
2009 OCT 19 ... levels and angiotensinogen, angiotensin-converting enzyme, angiotensin receptor type 1 (AT1), AT2, and Mas mRNA expression were lower as compared with the nonpregnant subjects. In ...
2009 SEP 7 ... and in patients. The purpose of this study was to investigate whether losartan (LOS), an AT1 receptor antagonist, reduces lung damage by inhibiting the induction of high mobility group box 1 ...
2009 NOV 9 ... the United States, "Agonistic autoantibodies to the angiotensin II type I receptor (AT1-AA) and endothelin -1 (ET-1) are suggested to be important links between placental ...
2009 SEP 14 ... m) also induced concentration- dependent calcium transients, which were attenuated by AT1 receptor inhibition. Simultaneously applied Ang II (10(-10) m) additively enhanced the calcium ...
2009 AUG 24 ... and this downregulation was further promoted by CV-11974, a specific antagonist of AT1 receptor. In contrast, the PD123319 compound, which selectively curtails the AT2 receptor, ...
2009 OCT 19 ... as Ang II protein, but did not affect the ACE mRNA level. ADT up-regulated angiotensin AT1 receptor mRNA, but not that of the AT2 receptor. The angiotensin...
2009 SEP 21 ... of cardiac hypertrophy. The contribution of the angiotensin II type 1 receptor (AT1) in angiotensin II-induced cardiac hypertrophy is well established, but the role of AT2 ...
