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2009 SEP 28 ... of patients with newly diagnosed APL are currently treated with all-trans retinoic acid (ATRA) plus anthracycline-based chemotherapy, typically followed by maintenance with...
2009 NOV 23 ... by binding to its molecular target more selectively than all trans-retinoic acid (ATRA), the current first-line treatment for APL. The FDA has granted Orphan Drug Designation ...
2009 SEP 14 ... single agent to adult patients following treatment failure with all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO). A durable complete response is achieved when no leukemia ...
2009 NOV 23 ... of non-melanoma skin cancer. We have determined the effects of all-trans retinoic acid (ATRA), a naturally occurring chemopreventive retinoid, on signal transducer and activator of ...
2009 JUL 22 ... were given 100 mu g (low-dose) or 1,000 mu g (high-dose) all-trans retinoic acid (ATRA)/kg body weight in corn oil or corn oil alone per os on days after inoculation (DAI) -1, ...
2009 AUG 3 ... the United Kingdom, "Vitamin A derivatives, including all-trans-retinoic acid (ATRA), have a well-established role during skeletal development and limb formation and have ...
2009 JUL 20 ... 'Regulation of CD11b transcription by decreasing PRC2 and increased acH4 level during ATRA-induced HL-60 differentiation,' have been published. "Polycomb repressive complex 2 ...
2009 NOV 9 ... slit diaphragm in the glomerulus. We previously reported that all-trans retinoic acid (ATRA) and 1,25-dihydroxyvitamin D-3 [1,25(OH)(2)D-3] induced expression of nephrin in murine ...
2009 JUL 27 ... have attempted to understand the chemopreventive mechanism of all-trans retinoic acid (ATRA), a primary biologically active retinoid, in order to more efficiently utilize retinoids ...
2009 NOV 23 ... heavy chain promoter-driven reporter (MyHC-GLuc), we have demonstrated that either ATRA or 9CRA is able to effectively induce myogenic differentiation, which can be ...
2009 AUG 31 ... of rosiglitazone (RGZ) alone as well as in combination with all trans-retinoic acid (ATRA) on human myeloma cell lines and try to address its potential mechanism," investigators ...
2009 NOV 23 ... only in cell lines that differentiate along this lineage after all-trans retinoic acid (ATRA) exposure. Forced PRAME expression in normal hematopoietic progenitors, however, ...
2009 AUG 31 ... leukemia, who developed acute respiratory failure from all-trans-retinoic acid (ATRA) syndrome. We applied noninvasive ventilation (NIV, continuous positive airway pressure ...
2009 NOV 2 ... major advance in the field of APL treatment has been the use of all-trans-retinoic acid (ATRA). Advances in the treatment of APL have taken this form of AML from a disease with ...
2009 JUL 27 ... used as a model for studying granulocytic differentiation. All-trans retinoic acid (ATRA) treatment of HL-60 cells promotes granulocytic differentiation and is effective as ...
2009 SEP 28 ... of the present study was to elucidate the mechanism by which all-trans retinoic acid (atRA) induces the cleft palate," investigators in Guangzhou, People's Republic of China ...
2009 AUG 31 ... kinase (ERK) signaling pathways. Interestingly, all-trans retinoic acid (ATRA) treatment induced potent cell death and growth inhibition in RAR alpha 2(+) but not RAR ...
2009 JUL 20 ... case of PML/RARA, this repression can be reversed through treatment with all-trans RA (ATRA), leading to leukemic remission," researchers in Marseille, France report. ...
2009 NOV 9 ... in the European Journal of Immunology, "We recently found that all trans retinoic acid (ATRA) accelerated B lymphocyte formation. In the current study, we address the question ...
2009 SEP 28 ... subtype of acute leukemias in adults due to the inclusion of all-trans-retinoic acid (ATRA) in the treatment," scientists in Olomouc, Czech Republic report. ...
