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2009 NOV 16 ... G alpha(i) isoforms, G alpha(i1), G alpha(i2), and G alpha(i3), in typical alpha(2)-adrenoceptor-controlled functions. Mice with targeted deletions in the genes encoding G alpha(i1), G ...
2009 OCT 19 ... pica model were confirmed in a second surrogate model of emesis, reversal of alpha(2)-adrenoceptor-mediated anesthesia in the mouse. The rank order of therapeutic indices derived in the ...
2009 NOV 2 ... (DCM) and to determine the tolerance and efficacy of a high dose of the beta(1)-adrenoceptor antagonist metoprolol in the long-term treatment of DCM patients. The prevalence of ...
2009 OCT 26 ... According to recent research published in the British Journal of Anaesthesia, "alpha(2)-Adrenoceptor agonists are currently used as primary sedative agents in high dependency patients who ...
2009 NOV 16 ... (PDE1-5). Catecholamines produce surges of inotropically relevant cAMP through beta(1)-adrenoceptor stimulation. cAMP is mainly hydrolysed by PDE3 and/or PDE4 thereby blunting ...
2009 OCT 19 ... system (CNS) penetrant, potent, selective, partial agonist at the human alpha 1(A)-adrenoceptor, demonstrating efficacy and selectivity in a range of binding and functional assays. In ...
2009 NOV 9 ... Current study results from the report, 'Increased alpha-1 adrenoceptor expression in pregnant rats with subrenal aortic coarctation,' have been published. ...
2009 NOV 23 ... Our aim was to study whether an insertion/deletion (I/D) polymorphism in the alpha(2B)-adrenoceptor gene is associated with the risk for sudden cardiac death. This was a prospective ...
2009 NOV 9 ... to exert their local anesthetic activity. We investigated cutaneous anesthesia from adrenoceptor agonists and/or antagonists in conscious, unanesthetized Sprague-Dawley male rats ...
2009 NOV 9 ... by 4-fold (from 120 to 480 min), which was reversed by pretreatment with the alpha-2 adrenoceptor inhibitor, yohimbine, and the mu-type opioid receptor antagonist, naloxone. ...
2009 NOV 1 ... to a study from Alexandria, Egypt, "We previously reported that nicotine impairs P-adrenoceptor-mediated renovascular control in male rats. Here, we investigated the roles of sex and ...
2009 NOV 9 ... did not affect the noradrenaline concentration-response curves except for the alpha-adrenoceptor antagonists. These results led to the conclusions that neurogenic contractions in the ...
2009 NOV 2 ... of gestational age; and (ii) the uterotonic and tocolytic actions of alpha- and beta-adrenoceptor stimulation, respectively. The effects of oxytocin in late pregnancy were also ...
2009 NOV 1 ... Cardiovascular Research, "Extensive clinical studies have demonstrated that beta-adrenoceptor blocking agents (beta-blockers) are beneficial in the treatment of chronic heart ...
2009 OCT 19 ... could serve as pathological basis for arrhythmogenesis and cardiac impairment by beta-adrenoceptor stimulation. We hypothesized that dispersed NADPH oxidase, protein kinase C epsilon (PKC ...
2009 NOV 9 ... fluoxetine and imipramine (1 nM-10 mc M) on the tension induced by the alpha(1)-adrenoceptor agonist NE (10 mc M) of SV strip preparations were studied using the organ bath ...
2009 OCT 20 ... Sciences (Effects of dexamethasone on the expression of beta(1)-, beta(2)- and beta(3)-adrenoceptor mRNAs in skeletal and left ventricle muscles in rats. Journal of Physiological Sciences, ...
