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2009 NOV 23 ... monitoring. If liver function test abnormalities are = Grade 3, omit or modify dose. AdverseReactions: The most common adversereactions observed in PROPEL were mucositis (70%), ... from the Company's pivotal PROPEL study, which served as the basis for U.S. Food and Drug Administration's accelerated approval of FOLOTYN™ on September 24, 2009, for the ...
2009 NOV 23 ... 50 percent of early NSCLC.1 In the Phase II clinical study, the most commonly reported adverse events were mild local (pain, redness, swelling) or systemic (fever, fatigue, muscle ... Ecology, Environment, Chemotherapy, Clinical Research, Clinical Trial Research, Drug Therapy, Immunotherapy, Infectious Disease, Lung Neoplasms, Non-Small Cell Lung Cancer, ... were mild local (pain, redness, swelling) or systemic (fever, fatigue, muscle pain) reactions. Out of 182 patients, only three Grade 3 adverse events were rated as possibly related ...
2009 NOV 23 ... patients, GBCAs have a favorable safety profile, with the majority of any adversereactions in this class being mild and usually transitory. A possible relationship, ... Inc., a Covidien company, has submitted this label change to the U.S. Food and Drug Administration (FDA) and is implementing the new label in the U.S. effective ...
2009 NOV 23 ... the globe nurses are administering vasoactive drugs with the constant risk of potential adverse drug reactions and medication errors. Vasoactive drugs are very potent and are typically ...
2009 NOV 23 ... and referral or consultation delays. Results further showed that adverse outcomes in 28 percent of the 583 reported cases were major, meaning that they resulted ... diagnosis. The most common missed or delayed diagnoses include pulmonary embolism, drugreactions or overdose, lung cancer, colorectal cancer, acute coronary syndrome, ...
2009 NOV 23 ... was reduced from 3.3 +/- 4.4 to 0.6 +/- 1.6 U/wk (P <.0001). Seventy-eight cases of adverse drug reactions were reported. The most common adverse drug reactions ...
2009 NOV 23 ... abnormality of TYMS are potential causative factors for a significant portion of serious adversereactions to 5-FU-based therapy." Shahrokni and colleagues published their ... to significant morbidity. Hand-foot syndrome seems to be dose dependent, and both peak drug concentration and total cumulative dose determine its occurrence," wrote A. Shahrokni ...
2009 NOV 23 ... P40 and Melan-A/Mart-1 peptide subcutaneously in monthly intervals." "Adversereactions were mild-to-moderate. Fourteen patients received at least 8 vaccinations and ... PA 19106-3621, USA. Keywords: City:Lausanne, Country:Switzerland, Drug Development, Immunization, Immunotherapy, Infectious Disease, Klebsiella pneumoniae, ...
2009 NOV 16 ... Seizures and other central nervous system (CNS) adverse experiences have been reported during treatment with INVANZ. As with other ... should be adjusted accordingly. To reduce the development of drug-resistant bacteria and maintain the effectiveness of INVANZ and other antibacterial ... or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams. Due to the use of lidocaine HCl as a diluent, INVANZ ...
2009 NOV 16 ... have hypersensitivity to the drug or any of its components. The most commonly reported adversereactions (incidence ≥ 2 percent) in CINV trials with palonosetron were headache ...
2009 NOV 19 ... "For the glabellar region, severe partly vascular adverse events have been reported after treatment with injectable fillers. For this study, data ... Malden 02148, MA, USA. Keywords: Germany, Berlin, Life Sciences, Adverse Drug Event, Adverse Drug Effect, Adverse Drug Reaction, Therapy, Treatment, Surgery, ... study, data from the Injectable Filler Safety Study, a German-based registry for those reactions, was analyzed to characterize adverse events seen in the glabellar region. were analyzed ...
2009 NOV 17 ... higher prices are not necessarily justified. Finally, doctors get information regarding adverse drug reactions primarily from the National Organisation for Medicines. However, it is notable that the ...
2009 NOV 23 ... compounds are safer and healthier than their synthetic counterparts, a large number of adverse cutaneous effects of plant extracts, notably contact sensitization, have been reported ... St., Malden 02148, MA, USA. Keywords: City:Ferrara, Country:Italy, Adverse Drug Effect, Adverse Drug Event, Adverse Drug Reaction, Dermatology, Therapy, Treatment, ... and type of topical botanical preparations used and occurrence of skin adverse reactions. Two hundred forty-one patients (60.25%) reported use of natural topical products, ...
2009 NOV 16 ... influence leflunomide pharmacokinetics, treatment response, and the occurrence of adverse drug reactions (ADRs). The study included 67 patients with RA and 4 patients with polyarthritis ...
2009 NOV 16 ... more developed research cohorts more efficiently and effectively." "Many adverse drug reactions are likely related in some way to genetic differences among patients," said Robert ...
2009 NOV 16 ... of hepatic encephalopathy (HE). The results demonstrate the rates and spectrum of adverse events (AEs) were similar in rifaximin-treated patients compared with patients receiving ... in the rifaximin group than the placebo group experienced severe AEs (26% vs 31%), drug-related AEs (19% vs 21%), serious AEs (36% vs 40%) and AEs leading to discontinuation ... anal discomfort, thirst, nausea and abdominal pain were some of the most common adverse reactions to MOVIPREP administration. Vomiting occurred less frequently. About ...
2009 NOV 16 ... The in-depth interviews indicated that financial burdens and extra medical expenditures, adverse drug reactions, and social stigma were additional potential factors accounted for non-adherence. More ...
2009 NOV 16 ... states, "In this 6-month, open-label adolescent extension study, we found that most adverse events were generally mild to moderate in intensity. Additionally, Daytrana treatment ... continuously while applied to the skin. Daytrana is approved by the US Food and Drug Administration (FDA) for a wear-time of nine hours; however, the patch can be removed ... seen in studies of oral methylphenidate in adolescents, with the exception of dermal reactions. The long term extension study evaluated four doses of the Daytrana patch worn for nine ...
2009 NOV 16 ... Varenicline was generally well-tolerated in the study. Treatment-emergent serious adverse events occurred in 2.8 percent of study participants treated with varenicline compared ... Clinical Trials, Pharmaceutical, Other Health, Research, Science, Psychiatric, Adverse Drug Effect, Adverse Drug Event, Adverse Drug Reaction, Chronic Bronchitis, Chronic ... may worsen while taking varenicline. Some people can have serious skin reactions while taking varenicline, some of which can become life-threatening. These can include ...
2009 NOV 17 ... and validation of an assay that will aid in the evaluation of patients who have suffered adverse drug reactions, particularly skin reactions. The presentation will take place at 1:30 p.m. on Sunday, ...
