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2009 DEC 1 ... "The mechanism underlying the handling of protein and peptide drugs such as insulin in alveolar epithelial cells is still unclear. We therefore examined fluorescein isothiocyanate-labeled ...
2009 NOV 24 ... visceral pleura or septal-pleural junctional region. These cysts were partly abutting alveolar structures, and lined by a layer of alveolar epithelium. These unique microscopic ... showed the localization of folliculin, the BHD gene-encoding protein, in macrophages and epithelialcells in the patient's and normal control's lungs. Haploinsufficiency of folliculin ...
2009 NOV 27 ... proteins showed that both MCT1 and MCT2 were basolaterally localized on the cow mammary alveolar epithelial cells. In contrast, MCT4 protein signal was expressed on the apical membrane of these alveolar ...
2009 NOV 16 ... in the epithelialcells of the bronchial wall and weaker in the epithelialcells of the alveolar sacs by in situ hybridization and immunohistochemical analysis. Furthermore, the mimecan ...
2009 NOV 9 ... "Enhancing gene delivery and expression in alveolar epithelial cells could offer the opportunity for the treatment of acquired and inherited lung diseases. ...
2009 NOV 16 ... acute renal failure. Here, we tested the therapeutic capacity of human MSCs to restore alveolarepithelial fluid transport and lung fluid balance from acute lung injury (ALI) in an ex ... "Recent studies have suggested that bone marrow-derived multipotent mesenchymal stem cells (MSCs) may have therapeutic applications in multiple clinical disorders including ...
2009 NOV 27 ... and structure were detected. A significant increase in respiratory burst function of alveolar macrophages points to a marginal inflammatory response. This can be explained by the ... in volume density of bronchial glands and a shift from neutral to acidic staining of epithelial secretory cells in distal airways. The acidic exposure had thus no pathophysiological ...
2009 NOV 30 ... cells (hASCs). The presence of hASCs inhibited MCF10A cell proliferation, induced both alveolar and ductal morphogenesis, and enhanced their functional differentiation as evidenced by ... "Epithelial-mesenchymal interactions play an important role in regulating normal tissue development ...
2009 NOV 16 ... "The conducting airways (bronchi and bronchioles) and peripheral gas exchange (alveolar) regions of the mammalian lung are generated by a process of branching morphogenesis. ... morphogenesis. Evidence suggests that during embryonic development, the undifferentiated epithelial progenitors are located at the distal tips of the branching epithelium." ... Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells.' According to recent research published in the journal Development, "The conducting ...
2009 NOV 3 ... with IPF. CCL22 levels in the BAL fluid did not correlate with the total cell numbers, alveolar lymphocytes, or macrophages in BAL fluid. However, the CCL22 levels significantly ... and CCR4 to CD68-positive alveolar macrophages as well as that of CCL17 to hyperplastic epithelialcells were shown. Clinically, CCL22 BAL fluid levels inversely correlated with DLco/VA ...
2009 NOV 9 ... benign and malignant breast tissue, with a stronger staining intensity in the peri-alveolar stromal cells of FIB at both mRNA and protein levels. Conversely, FLRG area and ... FLRG immunohistochemistry and in situ hybridization. The area and intensity of chromogen epithelial and stromal staining were analyzed semi-quantitatively. Follistatin and FLRG were ...
2009 NOV 30 ... results, 'Myosin-Va restrains the trafficking of Na+/K+-ATPase-containing vesicles in alveolar epithelial cells,' are detailed in a study published in Development. "Stimulation of Na(+)/K(+)-ATPase ...
2009 NOV 16 ... on respiratory cell lines and in vitro efficacy against Mycobacterium bovis in alveolar macrophages.' According to a study from Songkhla, Thailand, "Rifampicin-encapsulated ... liposomes were evidently nontoxic to respiratory associated cells, including bronchial epithelialcells, small airway epithelial and alveolar macrophages (AMs). Furthermore, the ...
2009 NOV 23 ... polymer-coated glass surface by means of photocatalytic lithography, and A549 (a human alveolarepithelial cell line), Hep G2 (a human hepatoma cell line) and mouse fibroblast 3T3 ... epithelial cell line), Hep G2 (a human hepatoma cell line) and mouse fibroblast 3T3 cells were inoculated onto the superhydrophilic regions. The cell populations were confined in ...
2009 NOV 16 ... transition (EMT) in the intratracheal bleomycin model." "Primary type II alveolar epithelial cells were cultured from Immortomice and exposed to transforming growth factor-beta(1) and ...
2009 NOV 2 ... chain reaction and ELISA we showed that LPS-activated alveolar macrophages stimulated alveolar epithelial cells (AEC) to express growth factors, particularly GM-CSF, in coculture. Antibody ...
2009 NOV 16 ... proliferation of junctional epithelium and inhibited induced systemic H2O2 levels and alveolar bone loss in vivo," wrote D. Ekuni and colleagues, University of British Columbia. ... tissue of origin. A rat periodontal disease model was used to study ROS-induced chronic epithelial inflammation and bone loss." "Lipopolysaccharide (LPS) was applied for 8 ... via elevated MAO/B-mediated increases in H2O2 and TNF-alpha activity by epithelial cells and is further associated with more distant effects on systemic oxidative stress and ...
