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2009 NOV 9 ... of SLFN2 form more colonies in soft agar, implicating this protein in the regulation of anchorage-independentgrowth," wrote E. Katsoulidis and colleagues, Northwestern University. ...
2009 NOV 23 ... that chemically modified dextrans inhibit SDF-1/CXCL12-mediated in vitro chemotaxis and anchorage-independent cell growth in a dose-dependent manner. The binding of GAG mimetics to the ...
2009 NOV 16 ... Furthermore, we found that overexpression of UBE2Q2 affects cell proliferation and anchorage-independent cell growth," wrote H. Maeda and colleagues, Hokkaido University, Medical ...
2009 NOV 9 ... cancer-derived mutants of cyclin D1 are much more stable than wild-type cyclin D1 under anchorage-independent conditions and possess a greater antagonistic effect on FOXO-regulated ... a greater antagonistic effect on FOXO-regulated anoikis and anchorage-independent growth of cancer cells," wrote L. Gan and colleagues, University of Minnesota. ...
2009 OCT 5 ... properties such as loss of contact inhibition, growth-factor independence, and anchorage-independentgrowth. Conversely, knockdown of RCP in human breast cancer cell lines ...
2009 NOV 23 ... other carcinomas. Specifically, alpha(v)beta(3) expressed in carcinoma cells enhanced anchorage-independent tumor growth in vitro and increased lymph node metastases in vivo. These ...
2009 NOV 1 ... According to recent research from Madrid, Spain, "Anchorage-independentgrowth (AIG) of cancer cells requires escape from integrin-mediated signals. ...
2009 OCT 19 ... GLUT-1. Furthermore, KLF5 expression was significantly elevated by high cell density, by anchorage-independent cell growth, and in tumor spheroids," wrote A. Mori and colleagues, Johann ...
2009 OCT 12 ... association between NK4 and perlecan impairs fibronectin assembly, thereby inhibiting anchorage-dependent signaling," wrote K. Sakai and colleagues, Osaka University. The ... factor-induced DNA synthesis, indicating that anti-angiogenic action of NK4 is c-Met-independent. Affinity purification with NK4-immobilized beads revealed that NK4 binds to perlecan. ... "NK4, a fragment of hepatocyte growth factor (HGF), exerts bifunctional action as a competitive antagonist against HGF and its ...
2009 NOV 16 ... the involved mechanisms. Depletion of PSMA7 by shRNA in RKO cells inhibited their anchorage-independentgrowth and cell invasion and migration. Moreover, PSMA7 depletion was able ...
2009 NOV 9 ... and lymphatic infiltration. Down-regulated LIV-1 cells showed significant inhibition of anchorage-dependent or -independent proliferation and cell motility in vitro and reduction of ... or -independent proliferation and cell motility in vitro and reduction of tumor growth and metastasis in vivo. Furthermore, nuclear expression of Snail was decreased and ...
2009 NOV 16 ... of the synovial sarcoma cell lines HS-SYII, SYO-1, and Fuji as well as prevented anchorage-independentgrowth. Conversely, reconstitution with CrkII by authentic small interfering ...
2009 NOV 9 ... cell growth rate increased gradually, along with tumor forming potential in in vitro anchorage-independentgrowth assays and in vivo tumor formation assays in immuno-deficient mice. ...
2009 OCT 5 ... cells by RNA interference led to remarkable inhibition of cell proliferation, migration, anchorage-independentgrowth as well as tumorigenicity in nude mice. Strikingly, silencing of Cbp ...
2009 NOV 16 ... cell proliferation and survival." "Forced expression of TFF1 enhanced anchorage-independentgrowth and promoted scattered cell morphology with increased cell migration ...
2009 OCT 19 ... the context of oncogenic NRAS both full length Jdp2 and the shorter isoforms increased anchorage-independentgrowth," wrote M.H. Rasmussen and colleagues, Aarhus University. ...
2009 OCT 5 ... and xenograft tumor growth in vivo. Furthermore, cystatin D inhibited migration and anchorage-independentgrowth, antagonized the Wnt/beta-catenin signaling pathway, and repressed ...
2009 NOV 9 ... stably overexpressed cav1 clones were established." "Proliferation and anchorage-independentgrowth capacity in vitro were detected by ...
2009 NOV 2 ... burdens the process of scale up and hence their production capability." "Anchorage-dependent MDCK cells were converted to anchorage-independent cells, capable of growing ... concentration of 7 x 10(5) cells/mL while keeping close to 100% viability throughout the growth phase. In production experiments, the siat7e-expressing cells were infected with the ...
