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2009 NOV 23 ... from Takamatsu, Japan, "Recent studies indicate a role of chymase in the regulation of angiotensin II (AngII) formation in cardiovascular and renal tissues. We investigated a possible ... acid (50 mg/kg, twice a day, p.o.), or the selective AT(1)-receptor blocker olmesartan (10 mg/kg per day, p.o.) for 14 days. UUO-induced renal interstitial ...
2009 NOV 18 ... According to recent research from Beijing, People's Republic of China, "Angiotensin II (Ang II) has been recognized as an apoptosis inducer in podocytes, but the mechanism ... in podocytes, but the mechanism of apoptosis induced by Ang II is unclear. Transient receptor potential cation channel 6 (TRPC6) is a calcium channel located in podocyte membrane." ...
2009 NOV 23 ... aldosterone levels, which could result not only from decreased activity of the renin-angiotensin system (RAS), but also from impaired AVP-stimulated aldosterone release in the adrenal ... New research, 'Vasopressin regulation of blood pressure and volume: findings from V1a receptor-deficient mice,' is the subject of a report. "[Arg(8)]-vasopressin (AVP) has several ...
2009 NOV 23 ... and more likely to have a nonischemic etiology and a higher ejection fraction. Dose of angiotensin converting enzyme inhibitor (ACEI) was lower in the women, on average. The lower ACEI ... the women, on average. The lower ACEI dose may reflect the higher use of angiotensin II receptor blocker (ARB) in women. Both the peak VO2 and the 6-minute walk distance were ...
2009 NOV 17 ... endothelial dysfunction, and myocardial fibrosis, which depend in part on activation of angiotensin II (Ang II)-mediated pathways. However, mechanisms underlying crosstalk between Ang II ... II)-mediated pathways. However, mechanisms underlying crosstalk between Ang II type 1 receptor (AT(1)R) and mineralocorticoid receptor (MR) are mostly unknown." "We ...
2009 NOV 16 ... "Renin-angiotensin-aldosterone system (RAAS) polymorphisms such as the angiotensinogen-gene-M235T-, the ... the angiotensin-conversion enzyme (ACE)-gene I/D- and the angiotensin-II-type 1-receptor-(AT(1)R)-A1166C-polymorphism have been implicated in renal insufficiency and ...
2009 NOV 16 ... heart failure. Among patients with diabetes, adjusted odds ratios (ORs) of receiving angiotensin-converting enzyme (ACE) inhibitors and oral hypoglycemics in the FFS group were, ... with chronic heart failure, adjusted ORs of receiving ACE inhibitors, angiotensin-receptor blockers, and statins in the FFS group were, respectively, 0.90, 0.78, and 0.79 (all ...
2009 NOV 16 ... effect is not fully understood. To test the hypothesis that SS may downregulate angiotensin type 1 receptors (AT(1)Rs)," scientists in Montreal, Canada report. ... published their study in Circulation Research (Shear Stress Regulates Angiotensin Type 1 Receptor Expression in Endothelial Cells. Circulation Research, 2009;105(9):869-U77). ...
2009 NOV 16 ... is unclear. To elucidate the mechanism how HGF and its receptor c-Met reduces angiotensin II (Ang II)-induced inflammation. HGF reduced Ang II-induced vascular smooth muscle cell ...
2009 NOV 16 ... a bundle of fixed doses of a generic statin and angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB), delivered with minimal outpatient visits, laboratory testing, and ...
2009 NOV 16 ... is a serious problem with a high risk of graft loss. The therapeutic role of renin-angiotensin-system (RAS) blockers in recurrent FSGS is not clear." "We present the ... safety and efficacy of an intensified triple RAS blockade with an ACE-inhibitor, an AT 1 receptor blocker and the direct renin inhibitor aliskiren in a 29-year-old renal transplant ...
2009 NOV 23 ... "Several studies have implicated the renin angiotensin system in the cardiac hypertrophy induced by thyroid hormone. However, whether ... the cardiac hypertrophy induced by thyroid hormone. However, whether Angiotensin type 1 receptor (AT(1)R) is critically required to the development of T-3-induced cardiomyocyte ...
2009 NOV 23 ... According to recent research from the United States, "The renin-angiotensin-aldosterone system (RAAS), an important regulator of blood pressure as well as fluid and ... RAAS with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-II (ANG-II) receptor blockers (ARBs) lowers blood pressure, decreases morbidity and mortality in patients ...
2009 NOV 23 ... classes examined were beta blockers (BB), angiotensin converting enzyme inhibitors or angiotensin receptor blockers (ACEI/ARB), nitrates, calcium channel blockers (CCB), and statins. In the Echo ...
2009 NOV 16 ... for brain angiotensin type 1 (AT(1)) receptors necessitates re-examination of brain angiotensin receptor binding studies." "To assess the ability of angiotensin II to bind to the ...
2009 NOV 23 ... of the renin angiotensin system using angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blocker (ARB) drug therapies has been shown to reduce blood pressure and associated ...
