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2009 JAN 12 ... nude mice. MDA-231-S10-bearing nude mice had a significantly poorer prognosis, and their bony metastatic tumors grew more rapidly than those of the mice bearing the parental cell ... publish new data in the report 'Matrix metalloproteinase-1 is a crucial bone metastasis factor in a human breast cancer-derived highly invasive cell line.' "Bone ...
2009 JAN 5 ... metastases during the course of their disease."
"However, distal bony involvement to the appendicular skeleton occurs less frequently, developing below the ... approximately 7% of metastatic renal cell carcinoma patients. The incidence of olecranon metastasis is extremely rare in all cancers and so far only two cases have been reported in ...
2009 OCT 5 ... T, weighted and short tau inversion recovery sequences). The number and sites of bony metastases were assessed on each imaging investigation independently. Sites of ... were assessed on each imaging investigation independently. Sites of extra-osseous metastasis on MRI were also noted. The imaging findings were correlated with other imaging ...
2009 JUN 29 ... the lungs, and the peritoneum," scientists in Nice, France report.
"Bony metastases are uncommon and of unknown prognosis. A 57-year-old man presented with ... a tyrosine kinase inhibitor, led to a partial response of the primary tumor and hepatic metastasis, but the patient developed aggressive bone metastases that proved refractory to 3 ...
2009 NOV 16 ... shown a single area of intense tracer uptake in the proximal right radius and no other bony lesion was identified. Infectious processes were considered initially, but the clinical ... The researchers concluded: "Histopathologic examination confirmed a bone metastasis in the proximal right radius." Lin and colleagues published their study in ...
2009 NOV 2 ... of osteoclast function is now established as an important treatment strategy for bony metastases," wrote M. Kawatani and colleagues, RIKEN, Biology Department. ... abnormal activity is implicated in a variety of human bone diseases. In neoplastic bone metastasis, the bone destruction caused by osteoclasts is not only associated with the formation ...
2009 SEP 28 ... although it has been reported to involve regional lymph nodes and to invade local bony structures such as the temporal bone and temporomandibular joint. 6 The following is the ... indicates that tumors with a diameter smaller than 8 cm will not trap platelets.(5) Metastasis is not considered to be part of the natural history of this lesion, although it has been ...
2009 MAY 11 ... computed tomography and bone scintigraphy identified several further sites of bony involvement but no primary malignancy. The patient was referred for F-18 FDG PET/CT ... pain, which demonstrated a solitary lesion in the T2 vertebral body suspicious for a metastasis," scientists writing in the journal Clinical Nuclear Medicine report.
...
2009 MAR 30 ... for intensity modulated TMI treatment planning, including a boost treatment to areas of bony involvement. The delivered dose was estimated by using MVCT images from the helical ... to planned dose. Bone scan imaging had a higher sensitivity for detecting skeletal metastasis compared to MR imaging. However the bone scan lacked sufficient specificity in three ...
2008 MAY 19 ... identifiable primary, presenting as acute pancreatitis, hypercalcemia, and disseminated bony metastasis. Such presentation has been rarely reported before," wrote S. Dhar and colleagues, ...
2008 MAY 5 ... with antihuman CXCR4 antibody. We also evaluated the pathological grade, extent of bony metastasis, clinical response to hormonal therapy, and patient prognosis. CXCR4 was detected in ...
2008 OCT 13 ... "The spinal MPNST that develops from spinal nerve roots and secondary bony erosion is well-known entity. However, primary intraosseous MPNSTs of the spine are ... patient remained symptom-free for 30 months after surgery without local recurrence or metastasis. We report an intraosseous MPNST of the cervical spine. Complete surgical excision and ...
2008 AUG 11 ... then presented bilateral femur metastasis. She was administered the surgical excision of bony metastasis and adjuvant therapies including chemotherapy, palliative radiation, and hormone ...
2008 JUN 23 ... manner. Treatment with OPG-Fc in vivo inhibited growth of MDA-231 tumor cells in bony sites when given both as a preventative (dosed day 0) and as a therapeutic agent for ... OPG ratio, a condition which favors excessive osteolysis. In a mouse model of bone metastasis, RANKL protein levels in MDA-MB-231 (MDA-231) tumor-bearing bones were significantly ...
2008 APR 28 ... of 44 patients with bone metastases. The remaining patient had a solitary, asymptomatic bony metastasis in shaft of femur. BS was positive in all patients with bone metastases. There were 11 ...
2008 APR 7 ... a massive renal tumor associated with extensive retroperitoneal lymph node involvement, bony metastases and a right hip fracture."
"She was initially managed with ... with renal angiosarcoma, whereas the pathology of the para-aortic lymph node and bone metastasis revealed angiosarcoma only. In view of her cachexia and cytopaenia, emergency ...
2008 DEC 8 ... murine model of sinonasal malignancy that reproduces the intracranial extension, bony destruction, and spread along neural fascial planes seen in patients with aggressive ... extension, orbital invasion, bony invasion, perineural invasion, and distant metastasis. Statistical analysis was done to calculate P values with the Student's t test for ...
2008 APR 21 ... an osseous metastasis. We report on a case with an unusual presentation of ORN mimicking bony metastasis that should be taken note of by physicians."
"A 46-year-old woman who ...
