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2009 NOV 23 ... association studies (GWAS) have identified multiple common genetic risk variants for breastcancer among women of Asian and European ancestry. Investigating these genetic ... States, Breast Cancer, Breast Carcinoma, Cancer Epidemiology, Genetic Risk Factor, Genetics, Oncology, Women's Health, Vanderbilt University. This article was ...
2009 NOV 30 ... used three pairs of cell lines with normal and reduced filamin-A expression, including breastcancer and melanoma cells. We found that lack or reduction of filamin-A sensitizes cells ... State:NJ, Country:United States, BRCA2, Breast Cancer, Breast Carcinoma, DNA, Dentistry, Genetics, Oncology, Women's Health This article was prepared by Clinical Oncology ...
2009 NOV 30 ... in solid tumors, chronic lymphoproliferative disease, multiple myeloma, lung and breast cancers. "I am pleased to report that we have met our Phase I objectives ... cancers at the 2009 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston. This Phase I study of imetelstat as a single agent ... Cancer Vaccines, Chemicals, Chemistry, Clinical Trial Research, Clinical Trials, Drugs, Genetics, Health, Hematology, Multiple Myeloma, Myeloma, Oncology, Pharmaceutical, ...
2009 NOV 30 ... "The susceptibility gene for ataxia telangiectasia, ATM, is also an intermediate-risk breast-cancer-susceptibility gene. However, the spectrum and frequency distribution of ATM ... Tavtigian and colleagues published their study in American Journal of Human Genetics (Rare, Evolutionarily Unlikely Missense Substitutions in ATM Confer Increased Risk of ...
2009 NOV 30 ... of the p53 tumor suppressor gene is a common event in many types of tumors, including breast cancers. Mutant p53 (mtp53) protein is thought to promote tumor cell survival and ... mtp53 and induces cell death in vitro and in vivo in estrogen-responsive breast cancer cell lines that express mtp53 (BT-474, HCC-1428, and T47-D). Fluorescent staining with ... Breast Carcinoma, Cell Proliferation, Chemotherapy, Drug Resistance, Drug Therapy, Genetics, Oncology, Treatment, Tumor Suppression, Women's Health This article was ...
2009 NOV 23 ... on a linear ion trap was utilized to identify and compare serum proteins from breastcancer patients." "Three groups of 21 human sera, 7 from patients with ... Carcinoma, Breast Disease, Chromatography, Diagnosis, Diagnostics, Ductal Carcinoma, Genetics, Mass Spectrometry, Oncology, Proteomics, Women's Health, Shanghai Jiao Tong ...
2009 NOV 30 ... Epidemiological and experimental evidence has implicated estrogens in the etiology of breastcancer," scientists in Arica, Chile report. "To study environmental ... City:Arica, Country:Chile, Breast Cancer, Breast Carcinoma, Drugs, Epidemiology, Genetics, Malathion, Microsatellite Instability, Oncology, Pharmaceuticals, Therapy, Treatment, ...
2009 NOV 23 ... (atypical ductal hyperplasia and/or ductal carcinoma in situ) and invasive ductal breast carcinoma from 52 patients, together with pure lesions from 24 patients and 12 normal ... and this epigenetic change has been considered as a potential molecular marker for cancer. We examined the methylation status of nine genes (APC, CDH1, CTNNB1, TIMP3, ESR1, ... Carcinogenesis, Carcinoma in Situ, Ductal Breast Carcinoma, Ductal Carcinoma, Genetics, Hyperplasia, Oncology, Tumor Suppression, Women's Health. This article ...
2009 NOV 30 ... BRCA1 or BRCA2 gene is the best-established indicator of an increased risk of developing breastcancer. Sequence analysis of these genes is being used to identify BRCA1/2 mutation ... For more information, contact S.K. Sharan, National Cancer Institute, Mouse Cancer Genetics Program, Center Cancer Research, Bldg 560, Room 32-31C, 1050 Boyles St., Fort Detrick, ...
2009 NOV 30 ... variants of the CHEK2 gene, at least one of which, CHEK2*1100delC (SNP), associates with breastcancer," investigators in the United States report. "A mouse model in ... contact P.J. Stambrook, University of Cincinnati, College Medical, Dept. of Molecular Genetics, Cincinnati, OH 45267, USA. The publisher of the journal Proceedings of the ...
2009 NOV 23 ... homologous bovine proteins contained in the medium. Application of the strategy to two breastcancer cell lines led to the identification of proteins secreted in different amounts ... Life Sciences, Ligand Libraries, Proteomics, Biotechnology, Genomics, Genetics, Peptide, Proteins, Proteome Research, University of Lausanne. This article ...
2009 NOV 23 ... points and treatment conditions from immunosuppressed mice implanted with MCF-7 human breastcancer cells. The generated raw LC-MS data was used for pattern analysis and ... States, Biotechnology, Chromatography, Disease Biomarker, Drug Development, Genetics, Mass Spectrometry, Proteomics, Therapy, Treatment. This article was ...
2009 NOV 23 ... Research findings, 'The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression,' are discussed in a new report. ... New York, NY 10010-1707, USA. Keywords: United States, Baltimore, Breast Cancer, Breast Carcinoma, Diagnosis, Diagnostics, Ductal Carcinoma, Genetics, Germ Cell Cancer, ...
2009 NOV 23 ... According to a study from the United States, "Ionizing radiation-associated breastcancer risk appears to be modified by timing of reproductive events such as age at ... National Cancer Institute, Radiation Epidemiology Branch, Division Cancer Epidemiology & Genetics, National Institutes of Health, DHHS, 6120 Execut Blvd., EPS 7060, MSC 7238, Bethesda, ...
2009 NOV 30 ... significant associations between a family history of colorectal, lung, prostate, or breastcancer and PD risk. Interactions between melanoma family history and age, smoking, or ... Keywords: City:Boston, State:MA, Country:United States, Central Nervous System Disease, Genetics, Melanoma, Neurology, Parkinson Disease, Parkinson's Disease This article ...
2009 NOV 23 ... "In Asian and Asian-American women, soy consumption is associated with reduced breastcancer risk, perhaps due to its effects on estrogen production or metabolism. In a ... contact B.J. Fuhrman, National Cancer Institute, Division Cancer Epidemiology & Genetics, Epidemiology & Biostatistics Program, 6120 Execut Blvd., Room 5003, Rockville, MD ...
2009 NOV 23 ... aromatase inhibitors: what the general internist needs to know,' is now available. "Breastcancer patients represent the largest group of adult cancer survivors in the US. Most ... wrote S. Hong and colleagues, University of Chicago, Center for Clinical Cancer Genetics. The researchers concluded: "In both settings increased knowledge by the ...
2009 NOV 30 ... relationships between genotypes and disease-free survival (DFS) among women treated for breastcancer, as well as those who did not receive adjuvant chemotherapy," researchers in the ... DNA, Doxorubicin Hydrochloride, Drug Therapy, Drugs, Enzymes, Fluorouracil, Genetics, Genomics, Genotyping, Methotrexate Sodium, Myeloperoxidase, Oncology, Pharmaceuticals, ...
2009 NOV 23 ... According to recent research published in the journal BreastCancer Research and Treatment, "The p53 tumor suppressor gene has a central role in the ... USA. Keywords: Country:Sweden, Apoptosis, Breast Cancer, Breast Carcinoma, Genetics, Oncology, P53 Gene, Social Science, Tumor Suppression, Women's Health, University of ...
2009 NOV 23 ... According to a study from the United States, "HER2 amplification in breastcancer is associated with a more aggressive disease, greater likelihood of recurrence, ... contact B.S. Herbert, Indiana University School Medical, Dept. of Med & Molecular Genetics, Indianapolis, IN 46202, USA. The publisher of the journal Breast Cancer ...
