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2009 OCT 13 ... plates identified by the positive labelling of acetylcholine receptors by TRITC-alpha-bungarotoxin co-labelled with anti-synaptophysin antibody, but this figure fell by 30% in muscles ...
2009 JUN 8 ... acetylcholine receptor (nAChR) is well established as the principal high-affinity alpha-bungarotoxin-binding protein in the mammalian brain. We isolated carbachol-sensitive alpha...
2009 JUN 15 ... mice. The latter responses, having distinct kinetics, were completely blocked by alpha-bungarotoxin," wrote T.K. Mehta and colleagues, Drexel University, Department of Pharmacology.
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2009 NOV 10 ... antagonists. alpha-Conotoxins blocking muscle-type or alpha7 nAChRs compete with alpha-bungarotoxin. However, alpha-conotoxin ImII, a close homolog of the alpha7 nAChR-targeting ...
2009 AUG 17 ... whole-cell current recording. Receptor expression was measured with I-125-labeled alpha-bungarotoxin (I-Bgt) binding, laser scanning confocal microscopy, and total internal reflectance ...
2009 JUN 16 ... from wild-type and knockout mouse. The specificity of Alexa Fluor 488-conjugated alpha-bungarotoxin (Alexa-alpha Bgt) was demonstrated in binding to alpha 7-transfected cells inhibited by ...
2009 AUG 17 ... native rat alpha 7* nAChRs in rat hippocampus and cerebral cortex. We used [I-125]-alpha-bungarotoxin to compare ligand binding profiles in these cells with those in rat hippocampus and ...
2009 JUL 7 ... response that led to Ca2+ influx through L-type Ca2+ channels was inhibited by alpha-bungarotoxin and attenuated by nifedipine, and it was detected only in the dedifferentiated ...
2009 JUN 15 ... nicotinic acetylcholine receptor binding sites with the aid of radiolabeled [I-125]alpha-bungarotoxin. The effective D-tubocurarine concentration that decreased twitch responses by 50% ...
2009 NOV 16 ... ex vivo in contraction experiments. AChR levels were measured with I-125-alpha-bungarotoxin, and endplates were studied with quantitative immunohistochemistry. in normal muscles ...
2009 SEP 1 ... of acetylcholine to nicotinic and muscarinic acetylcholine receptors (AChRs: alpha-bungarotoxin, tubocurarine, atropine and, gallamine) and binding of ATP to P2Y receptors (suramin). ...
2009 JUN 22 ... gene transcription. Block of alpha 7 nicotinic acetylcholine receptor (nAChR) by a-bungarotoxin attenuated NNK-induced increase of contactin-1. We also found that NNK activated alpha 7 ...
2009 AUG 18 ... using single-channel patch-clamp recordings. Equilibrium and kinetic [I-125]alpha-bungarotoxin binding assays, as well as fluorescence microscopy using fluorescent alpha...
2009 NOV 2 ... time-course of the phospholipase A(2) activity (PLA(2)) hydrolysis of notexin, beta-bungarotoxin, taipoxin and textilotoxin acting in cultured neurons was determined. At variance from ...
2009 OCT 6 ... "Current fluorescent probes for alpha7 nicotinic ACh receptors are derived from alpha-bungarotoxin (alpha-BgTx). However, alpha-BgTx also binds to alpha9* and alpha1* receptors which are ...
2009 APR 27 ... (VAChT), and a classical postsynaptic marker for motor terminals, namely alpha-bungarotoxin. Muscle fibers were counter-stained with phalloidin. 3D reconstructions were done of ...
2009 MAY 25 ... readily blocks the channel resulting in paralysis. The molecular interaction of alpha-Bungarotoxin, a long chain alpha-neurotoxin from (Bungarus multicinctus) and human alpha(7)nAChR seas ...
2009 SEP 21 ... (SERT) and noradrenaline (NET) were assessed using [H-3]epibatidine, [H-3]alpha-bungarotoxin, [H-3]citalopram, and [H-3]nisoxetine binding, respectively. In the mFST, ...
2009 AUG 24 ... GT1a, and GD1b." "Neuromuscular junctions (NMJs) were detected by alpha-bungarotoxin binding and by acetyl cholinesterase reaction. Most motor endplates of human EOMs richly ...
2009 JUN 29 ... antibody was used for immunohistochemistry, and fluorescein isothiocyanate-labeled alpha-bungarotoxin, which binds specifically to the alpha 7nAChR, was used for immunofluorescence. Gene ...