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2009 APR 13 ... in the journal Gastroenterology, "Backgground & Aims: NK1.1(+) TCR alpha beta(int) CD1-restricted T (NKT) cells are a unique subset of T lymphocytes that are believed to have ...
2009 MAY 5 ... of antibody responses to pneumococcal capsular polysaccharides is independent of CD1 expression in mice.' "Streptococcus pneumoniae is a bacterial microorganism that ... report.
"The aim of the present study was to evaluate the role of CD1-restricted T cells in the antibody response to caps-PS. When immunized with Pneumo23, wild-type ...
2009 NOV 2 ... A report, 'Mycobacteria exploit p38 signaling to affect CD1 expression and lipid antigen presentation by human dendritic cells,' is newly published ... antigen-presenting molecules that present both microbial and self lipid antigens to CD1-restricted alpha/beta T lymphocytes. The production of high levels of gamma interferon and lysis of ...
2009 MAR 9 ... deficits induced by 6-hydroxydopamine (6-OHDA) lesions of dorsal striatum in CD1 mice. The results demonstrated that systemic injections of MPEP (6, 12, and 24 mg/kg, ... symptoms in the early stages of the disease when dopamine loss is moderate and still restricted to the caudate putamen. The metabotropic glutamate receptor 5 (mGluR5) antagonist, ...
2009 JUL 27 ... to or presented by molecules encoded in the major histocompatibility complex (MHC). The CD1 family of antigen-presenting molecules is related to the MHC-encoded molecules, but CD1 ... cells influence many immune responses, they have a T-cell antigen receptor (TCR) that is restricted in diversity, and they share properties with cells of the innate immune system. NKT ...
2009 APR 14 ... "CD1 proteins constitute a distinct lineage of antigen-presenting molecules specialized for ... in CD1d affect the presentation of endogenous and exogenous ligands to CD1d-restricted T cells, including type I (V alpha 14i) and type II (non-V alpha 14i) natural killer T ...
2009 AUG 31 ... inference, we tested skin xenograft survival in B6 CD1(null) mice because NKT cells are CD1 restricted. of these trials demonstrate that the absence of CD1(+) cells adversely affects rat skin ...
2009 JAN 27 ... "The molecular details of glycolipid presentation by CD1 antigen-presenting molecules are well studied in mammalian systems. However, little is ... open, 2-pocket architecture observed in mammalian CD1s. Potential antigens then would be restricted in size to single-chain lipids or glycolipids. An endogenous ligand, possibly palmitic ...
