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2009 OCT 27 ... Molecules and Cells, "Iron binding lactoferrin (Lf) is involved in the control of cellcycle progression. However, the molecular basis underlying the effects of Lf on cell ... The Lf(Fe3+)-induced phosphorylation of Cdk inhibitors impaired their nuclear import behavior, thereby inducing cell cycle progression. However, the treatment of cells with a PI3K ...
2009 AUG 24 ... "Recurrent intrathoracic thymomas may have an unpredictable behavior. Cell-cycle protein expression has proven useful in predicting outcome in a variety of ...
2009 OCT 13 ... France report. "Here we show that mitochondria re-organize during the cellcycle and that this process is both dynamin- and microtubule-dependent. Microtubule ... of Toulouse. The researchers concluded: "Mitochondrial ends exhibit motile behavior, extending towards and retracting from the cell poles, independently of the ...
2009 OCT 12 ... that were expected to produce truncated proteins, resulting in loss of control of the cellcycle, provided additional support for OKCs having a neoplastic nature," scientists in ... "The aggressive biological behavior of odontogenic keratocysts (OKCs), unlike that of other odontogenic cysts, has argued ...
2009 SEP 7 ... of Pax6 at the onset of neurogenesis using Emx1-Cre line resulted in premature cellcycle exit of early progenitors, increase of early born neuronal subsets located in the ... The researchers concluded: "Because a majority of the morphological and behavior disabilities of the Pax6 mutant mice parallel abnormalities reported for aniridia ...
2009 SEP 22 ... "Src-family kinases (SFKs) play a pivotal role in growth factor signaling, mitosis, cell motility and invasiveness. In their basal state, SFKs maintain a closed autoinhibited ... the present study, we show that the basic properties of the Src activation/deactivation cycle can bring about complex signaling dynamics, including oscillations, toggle switches and ... in the activation loop. The spatiotemporal dynamics of SFK activation controls cell behavior, yet these dynamics remain largely uninvestigated. In the present study, we show that ...
2009 NOV 16 ... of the polycomb repressive complex 2. Polycomb repressive complex 2 controls numerous cellcycle and regulatory genes through trimethylation of histone 3, which results in ... vitro colony formation. Furthermore, EZH2 transformation resulted in increased invasive behavior of BPH1 cells, indicating that EZH2 may be responsible for aggressive behavior in ...
2009 SEP 14 ... in less intense ones. In addition, a significant portion of the oriC regions at this cellcycle stage had no colocalized DnaA-enhanced yellow fluorescent protein (EYFP) focus ... role in the initiation of DNA replication." "In order to monitor its behavior in living Escherichia coli cells, a nonessential portion of the protein was replaced by ...
2009 SEP 14 ... staining), morphology (scanning electron microscopy), proliferation (picogreen assay), cellcycle assay (propidium iodide staining), and differentiation (alkaline phosphatase [ALP] ... and chemical stimulus provided by the matrix is indispensable to determine the cellular behavior. This study has investigated the influence of platelet-rich plasma (PRP) and fibrin glue ...
2009 NOV 9 ... that trigger this response. Notably, this paper and a subsequent report ( Ayoub et al. CellCycle 2009; 8: 1494-500), demonstrate that transient HP1 beta mobilization is followed ... HP1 recruitment to damage sites, rather than its rapid mobilization, is the predominant behavior exhibited by this protein. Here, we present new experimental analyses which corroborate ...
2009 AUG 24 ... virus of about 9.6 kb. Like all enveloped viruses, the HCV membrane fuses with the host cell membrane during the entry process and thereby releases the genome into the cytoplasm, ... and thereby releases the genome into the cytoplasm, initiating the viral replication cycle." "To investigate the features of HCV membrane fusion, we developed an in ... role played by the E2 glycoprotein in the process of HCV fusion, and reveal an important behavior of HCV of different densities with regard to fusion.." Haid and colleagues ...
2009 AUG 25 ... France. The publisher of the journal Current Biology can be contacted at: Cell Press, 600 Technology Square, 5TH Floor, Cambridge, MA 02139, USA. ... discharge is responsible for instigating the motor pattern underlying each radula. bite cycle. We report that the sporadic production of biting patterns in preparations from naive ... learning, produces a long-lasting switch in the mollusk Aplysia's food-seeking behavior from irregular, impulsive-like radula biting movements into stereotyped, compulsive-like ...
2009 OCT 12 ... Netherlands. Publisher contact information for the Biophysical Journal is: Cell Press, 600 Technology Square, 5TH Floor, Cambridge, MA 02139, USA. ... modality was used to record fluorescent images during the stretching and relaxation cycle." "Force extension curves recorded in the presence of either dye did not ... microscopy imaging into an optical tweezers set-up and studied the force extension behavior of individual DNA molecules in the presence of various YOYO-1 and YO-PRO-1 ...
2009 SEP 28 ... transcription-PCR. Functional and genomic techniques revealed that alterations in cellcycle, repair, detoxification, and stress response pathways could be involved in the ... for some constitutive molecular mechanisms that in a basal manner may influence the behavior of HD patients," scientists in Madrid, Spain report. "We aimed to ...
2009 OCT 19 ... Scientists discuss in 'Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cellcycle arrest, cell ... the largest subgroup. However, the molecular mechanism underlying its malignant behavior and progression is not clarified," scientists writing in the journal Oncology Reports ...
2009 OCT 5 ... "Multicellular organisms shape development and remove aberrant cells by programmed cell death (''apoptosis''). Because defective cell death (too little or too much) is ... model to study p53-induced cellular responses to DNA damage. Cells first undergo cell cycle arrest and DNA repair, and then apoptosis if the damage is beyond repair," wrote T.L. ... commitment to positive feedback in the executioner module. The model accounts for the behavior of mutants deficient in various genes and is used to design experiments that would test ...
2009 SEP 29 ... and behavioral factors. Accumulating evidence supports a role for different cellcycle inhibitors in mammalian aging." "Little is known, however, about ... 5TH Floor, Cambridge, MA 02139, USA. Keywords: Singapore, Life Sciences, Behavior, Aging, Developmental Science, Cell Biology. This article was prepared by ...
2009 NOV 1 ... "p21 (Cyclin-dependent kinase inhibitor-1A, CDKN1A or CIP1) plays a role in regulating cellcycle, and its expression is lost in most colorectal cancers. p21 Is related with energy ... cellular senescence, and stem cell aging. Thus, the influence of p21 loss on tumor behavior and clinical outcome may be modified by patient age and body mass index (BMI)," ...
2009 OCT 19 ... ability to choose, compete for and retain her preferred mate? A new paper published by Cell Press in the October issue of the journal Trends in Ecology and Evolution reviews ... Human females are only fertile for a brief period during their menstrual cycle, just prior to ovulation. Many scientific studies have established that partner ... Lummaa. Keywords: Oral Contraceptives, Conservation, Ecology, Environment, Behavior, Contraception, Gynecology, Menstruation, Obstetrics, Oral Contraceptive, Pregnancy, ...
