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2009 NOV 9 ... "Using CD11c diphtheria toxin receptor-green fluorescent protein -> C57BL/6 BM chimeric mice, which allow for sustained ablation of DC with diphtheria toxin, we confirmed the ...
2009 NOV 23 ... ECD was re-engineered by fusion of the receptor protein to the carboxyl terminus of the chimeric monoclonal antibody (mAb) to the human insulin receptor (HIR). The HIRMAb-TNFR fusion ...
2009 NOV 16 ... models: laser occlusion of retinal vessels in adult green fluorescent protein (GFP) chimeric mice and oxygen-induced retinopathy in mouse pups. Intravitreal injection of ...
2009 NOV 9 ... containing nine residues with potent MMP-inducing properties on isolated mitochondria. A chimeric peptide composed of a Tat-PTD linked to the 9-mer entity triggers MMP and cell death. ... infection triggers apoptosis especially through the expression of the small membrane (M) protein," scientists in London, the United Kingdom report. "Using isolated ...
2009 NOV 10 ... activity from amino acids 51 to 167. Interestingly, this region drives the export of a chimeric nuclear protein in a cell cycle-regulated pattern similarly to that observed for Whi5. ...
2009 NOV 16 ... improve in vivo DMD splice correction. Here we report for the first time that a chimeric fusion peptide (B-MSP-PMO) consisting of a muscle-targeting heptapeptide (MSP) fused to ... (DMD) is caused by mutations in the DMD gene that abolish the synthesis of dystrophin protein. Antisense oligonucleotides (AOs) targeted to trigger excision of an exon bearing a ...
2009 NOV 9 ... Keywords: United States, Madison, Bioengineering, Biological Chemistry, Biotechnology, Chimeric Protein, Enzyme Research, Medical Device, Polymerase, Proteomics, University of Wisconsin. ...
2009 NOV 17 ... and colleagues. The researchers concluded: "Results with a panel of chimeric forms of gB, in which portions of the glycoprotein bracketed by consecutive cysteines ... has been detected only in the presence of gD by means of a split green fluorescent protein complementation assay. Here, we show that gB interacts with gH/gL in the absence of gD. ...
2009 NOV 16 ... transgenic bone marrow (BM)-derived cells found in the damaged liver of transplanted chimeric mice that underwent bile duct ligation." "Silencing of S1P(3) expression ... liver fibrosis. in addition, the S1P(3) receptor was also expressed in green fluorescent protein transgenic bone marrow (BM)-derived cells found in the damaged liver of transplanted ...
2009 NOV 16 ... significant homology with cochaperone p23, which regulates Hsp90 chaperone activity. The chimeric p23 in which the cochaperone domain was replaced with the p23-like domain of hB-ind1 ... "Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is a component of the replication complex consisting of several host and viral ...
2009 NOV 10 ... ( HA) gene and mutating the packaging regions in the ORF of the HA, we created a chimeric HA segment with the packaging identity of an NS gene. By the same strategy, we made an ... as in the terminal regions of the ORF of an RNA segment. By putting the nonstructural protein (NS)-specific packaging sequences onto the ORF of the hemagglutinin ( HA) gene and ...
2009 NOV 16 ... for the GRPR, which has been extensively studied." "To provide insight, chimeric NMBR-GRPR loss-of-affinity and gain-of-affinity mutants were made, as well as ... actions in many tissues, and their effects are mediated by two closely related G-protein-coupled receptors, the NMBR and GRPR. Little is known about the structural determinants ...
2009 NOV 16 ... activity, although NSP1 degradation was not required for IRF3 degradation. Using a chimeric RRV NSP1 protein containing the carboxyl 100 residues derived from UK NSP1, we found ...
2009 NOV 10 ... putida KT2440. It encodes for MrdH, a predicted protein of similar to 40 kDa with a chimeric domain organization derived from the RcnA and RND (for resistance-nodulation-cell ...
2009 NOV 3 ... by the G beta subunit of the heterotrimeric G-protein complex. Analysis of expressed chimeric MLO4/MLO2 proteins revealed that the C-terminal domain of MLO4 is necessary but not ...
2009 NOV 9 ... tyrosine kinase associated with a specific atypical myeloproliferative disease. The chimeric protein localizes to the cytoplasm, unlike the wild type FGFR1 receptor kinase, and presumably ...
2009 NOV 9 ... immunofluorescence microscopy using AgfA-specific antiserum verified the expression of chimeric AgfA; expression was also proved by a Congo red binding assay. Oral immunizations of ... cytotoxic T lymphocytes, was incorporated into the gene encoding AgfA (the major subunit protein of thin aggregative fimbriae of Salmonella) by replacing an equal length DNA segment. To ...
2009 NOV 9 ... of OprN( OprMN), and the second with these halves reversed ( OprNM). of either of the chimeric protein genes into a mutant expressing MexEF alone restored the functionality of the efflux ...
2009 NOV 4 ... able to induce protective immunity in experimental settings. Among these proteins, the chimeric and immunologically cross-reacting alpha-like proteins are particularly important," ... particularly important," scientists in Trondheim, Norway report. "Another protein, R3, which has been less well studied, occurred at a frequency of 21.5% in GBS from ...
