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2009 AUG 10 ... analog that incorporates characteristics of two other purine analogs, fludarabine and cladribine," scientists in the United States report. "It has shown efficacy in ...
2009 OCT 12 ... of a New Drug Application (NDA) to the US Food and Drug Administration (FDA) for Cladribine Tablets, EMD Serono's proprietary investigational oral formulation of...
2009 OCT 12 ... of a New Drug Application (NDA) to the US Food and Drug Administration (FDA) for Cladribine Tablets, Merck Serono's proprietary investigational oral formulation of...
2009 AUG 3 ... a marketing authorization application (MAA) to the European Medicines Agency (EMEA) for Cladribine Tablets, Merck Serono's proprietary investigational oral formulation of...
2009 SEP 21 ... of surveyed neurologists indicate they will prescribe Merck Serono/EMD Serono's oral cladribine for the treatment of multiple sclerosis. The new Physician & Payer Forum ...
2009 OCT 12 ... search we identified all patients with AML treated at Washington University with cladribine-based regimens. Twenty-four patients were identified that were treated with 2...
2009 NOV 2 ... cell leukemia (HCL) treatment is excellent, but evidence of cure with purine analogs cladribine and pentostatin, is lacking. Significant long-term immune suppression, particularly to ...
2009 AUG 3 ... based on blood counts." "were stratified into three groups: response to cladribine less than 1 year, those with a response lasting 1 to 4 years, or no response and ...
2009 NOV 2 ... The introduction of the two commonly used purine nucleoside analogs (pentostatin and cladribine, respectively) has independently changed the natural history of this rare malignancy." ...
2009 JUL 20 ... reviewed data retrospectively from 233 patients, treated with pentostatin (n = 188) or cladribine (n = 45), to investigate the current long-term outlook. Median follow-up was 16 years. ...
2009 AUG 24 ... Research findings, 'Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude ...
2009 NOV 2 ... early 1980s, when interferon-alfa and subsequently purine analogs (PAs) pentostatin or cladribine, or pentostatin were described to determine durable responses. However, second lines of ...
2009 AUG 24 ... to chlorambucil, cyclophosphamide, doxorubicin, mitoxantrone, corticosteroids, cladribine and fludarabine (p <0.01) but not to pentostatin. These results provide further ...
2009 AUG 3 ... "This randomized, 2-year, double-blind, placebo-controlled, crossover study evaluated cladribine for relapsing forms of multiple sclerosis. Patients (n = 84) received seven 5-day ...
2009 JUN 22 ... designed anticancer agents that disrupt DNA and RNA synthesis. Fludarabine and cladribine have important roles in the treatment of hematologic malignancies."
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2009 JUL 13 ... New investigation results, 'Phase I/II and pharmacokinetic study of cladribine with 2-h infusion in Japanese patients with relapsed indolent B-cell lymphoma mostly ...
