Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Google 2009 PageRank: #2 Among Top Health News and Media Publications
Google 2009 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2009 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2009 PageRank: #2 News and Media Site for the Pharmaceutical Industry
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
2009 AUG 17 ... damage present immediately after etoposide exposure is a good independent predictor of clonogenic survival. Our results also revealed that preexposure to hypoxia did not affect the ... results also revealed that preexposure to hypoxia did not affect the apparent DNA repair capacity of cells. These findings indicate that the extent of DNA damage resulting from etoposide ...
2009 JUN 1 ... MSC share similar properties with human and rodents MSC, including their capacity for clonogenic growth and multiple stromal lineage differentiation. In the present study, ovine bone ...
2009 MAY 11 ... clinical trials. Preclinical studies have also demonstrated that imetelstat can inhibit clonogenic growth of both primary myeloma patient samples and subpopulations from myeloma cell ... of NSCLC is targeted by the drug. Imetelstat Sodium (GRN163L) Diminishes Self Renewal Capacity and Decreases Tumorigenic Potential of Putative Cancer Stem Cells from Human Breast ...
2009 JUN 1 ... were mutated. These mutations do not impair the ability of AML1-ETO to enhance the clonogenic capacity of primary mouse bone marrow cells and do not eliminate its ability to repress ...
2009 SEP 28 ... of CD133(+) TSC cultures and established glioma cell lines was determined by clonogenic assay. The TSCs and established cell lines were also compared in terms of DNA ... cell lines were also compared in terms of DNA double-strand break (DSB) repair capacity and cell cycle checkpoint activation. Based on clonogenic analysis, each of the six TSC ...
2009 JAN 19 ... while maintaining undifferentiated cells by self-renewing cell divisions. The clonogenic progeny of an LG forming cell is capable of reconstituting hepatic tissues in vivo by ... into immunodeficient mutant mice. These data provide evidence for the stem cell-like capacity of isolated and clonally cultured CD133(+) LC-forming cells," wrote A. Suzuki and ...
2009 APR 6 ... proliferation and survival of murine Mll-AF9 leukemia cells. We also observed reduced clonogenic capacity and increased monocytic differentiation. The establishment of leukemia in ...
2009 APR 13 ... used to induce DNA double strand breaks in three MM cell lines."
"Clonogenic survival assays showed U266 (SF4=15.3+6.4%) and RPMI 8226 (SF4 = 12.6.0 + 1.7%) were ... reduction in rejoining fidelity compared to U266, with OPM2 showing an intermediate capacity. Ionizing radiation induced a robust gamma-H2AX response in OPM2 but only a modest ...
2009 JUL 27 ... mice contain a subpopulation of cells that show a neural precursor phenotype, clonogenic and multilineage differentiation capacity, activated Hedgehog signaling, wild-type ...
2009 APR 27 ... lethality and repopulating the culture, as evidenced by increased cell number, improved clonogenic capacity of viable cells, and normalization of DNA synthesis. Conversely, when cells were exposed ...
2009 FEB 2 ... and the in vivo therapeutic applications. In the present study, we compared the clonogenic and differentiation capacity of MSCs present in three BM-derived populations-namely, the ...
2009 NOV 2 ... The migration capacity Of the CPCs was determined with a boyden chamber and the clonogenic capacity by CFU-assay. In the ET-group the number and migration capacity of CPCs increased ...
2009 MAR 9 ... of melanoma in the context of a defined hyperthermic dose was evaluated in vitro. Clonogenic assays were used to measure cell survival. Gelatinase zymography determined secretion of ... sub-lethal hyperthermic treatment (41.8A degrees C for 2 h) suppressed tumor cell growth capacity as measured by clonogenic assay. The co-treatment also significantly suppressed tumor ...
2009 MAR 23 ... RNA interference knockdown of ASCL1 in cultured SCLC resulted in inhibition of soft agar clonogenic capacity and induction of apoptosis. cDNA microarray analyses bolstered by expression studies, ...
2009 JAN 5 ... the short-term growth of these cell lines. In three cell lines, Wnt3A promoted clonogenic cell recovery after suspension culture, suggesting the promotion of the self-renewal ... cell recovery after suspension culture, suggesting the promotion of the self-renewal capacity of leukemic stem or progenitor cells. Immunoblot analysis showed that Wnt3A stimulation ...
2009 JUL 20 ... report. "This study investigated key stem cell properties of individual clonogenic epithelial and stromal cells obtained from human endometrium. Single-cell suspensions of ... rare epithelial progenitors and MSCs, likely responsible for its immense regenerative capacity, which may also have critical roles in the development of endometriosis and endometrial ...
2009 JUN 8 ... with chemotherapy response. Overexpression of CTGF in MCF7 cells (MCF7/CTGF) enhanced clonogenic ability, cell viability, and resistance to apoptosis on exposure to doxorubicin and ... (MDA231) cells by antisense CTGF cDNA (MDA231/AS cells) mitigated this drug resistance capacity. CTGF overexpression resulted in resistance to doxorubicin- and paclitaxel-induced ...
2009 MAY 25 ... cells transduced with miR-223 showed a significant reduction of their erythroid clonogenic capacity, suggesting that downmodulation of this miRNA is required for erythroid progenitor ...
2008 DEC 8 ... Furthermore, HPCs transfected with MIRN155 showed a significant reduction of their MK clonogenic capacity, suggesting that down-modulation of this miRNA favours MK progenitor differentiation. ...
2008 DEC 29 ... compartment. The self-renewing capacity of this population was characterized using a clonogenic assay and a 3D organotypic culture model. The putative esophageal stem cells were also ...
