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2009 MAR 30 ... several inherited diseases associated with NER deficiencies: xeroderma pigmentosum, Cockayne syndrome, trichothiodystrophy, UV-sensitive syndrome," wrote T. Nouspikel and colleagues, ...
2009 FEB 9 ... upon the ability of lesions to arrest elongating RNA polymerase. In mammalian cells, the Cockayne syndrome a protein (Csb) mediates transcription-coupled repair, and its involvement in the repair ...
2009 MAR 2 ... and here we review the findings from our analysis."
"In cases of Cockayne syndrome, the oxidative products of lipids and proteins were increased in the globus pallidus; ...
2009 JUN 15 ... and defective cells. Furthermore, transcription coupled repair-deficient Cockayne syndrome cells are not hypersensitive to UVA/6-TG, indicating that potentially lethal ...
2009 APR 27 ... to be involved in the repair of psoralen ICLs [xeroderma pigmentosum (XP)-A, XP-C, XP-F, Cockayne's syndrome-B, Fanconi anemia] but did require the ataxia-telangiectasia and ...
2009 MAR 9 ... mutations at A: T base pairs. In the non-mutagenic pathway, we examined the role of the Cockayne syndrome B protein that interacts with other repair proteins," wrote H. Saribasak and ...
2009 JUN 1 ... According to a study from Rome, Italy, "Back Cockayne syndrome (CS; MIM 133540-216400) is a rare autosomal recessive neurodegenerative disorder ...
2009 MAY 4 ... early development of skin cancers. To diagnose patients with XP and the related disorder Cockayne syndrome (CS), our laboratory has established a simple autoradiographic method that examines ...
2009 JUN 1 ... According to recent research from the United States, "Cockayne syndrome (CS) is a premature aging condition characterized by sensitivity to UV radiation. ...
2009 AUG 31 ... According to recent research from Warsaw, Poland, "Cockayne syndrome complementation group B (CSB) protein is engaged in transcription-coupled repair (TCR) ...
2009 JUN 15 ... block progression of the transcription machinery in actively-transcribed regions of DNA. Cockayne syndrome ( CS) is another genetic disorder with sun sensitivity and defective TC-NER, caused by ...
2009 AUG 10 ... cause three different genetic conditions: xeroderma pigmentosum, trichothiodystrophy and Cockayne's syndrome. Crystal structures of XPD from three archaeal organisms reveal a ...
2009 APR 13 ... display the combined cancer and developmental-progeroid disorder xeroderma pigmentosum/Cockayne syndrome (XPCS). Due to the dual transcription repair role of XPB and the absence of animal ...
2009 FEB 2 ... (brittle hair with a tiger-tail banding pattern on polarized microscopy) or Cockayne syndrome (cachectic dwarfism, cataracts, pigmentary retinopathy and spasticity) were absent. ...
2008 DEC 8 ... for their role in ATR signalling, but not H2AX. Finally, the process is activated in Cockayne's syndrome but not Xeroderma pigmentosum group A cells providing evidence that ssDNA ...
2008 NOV 17 ... using cells from mouse models for the NER disorders xeroderma pigmentosum (XP) and Cockayne syndrome (CS). TC-NER-deficient Csb(-/-) and GG-NER/TC-NER-defective Xpa(-/-) MEFs are ...
2008 NOV 10 ... degradation was abrogated by the proteasome inhibitor MG132 and was dependent on TC-NER. Cockayne syndrome (CS) cells and xeroderma pigmentosum (XP) cells (XPD, XPA, XPG, and XPF) were defective ...
2008 DEC 8 ... degradation was abrogated by the proteasome inhibitor MG132 and was dependent on TC-NER. Cockayne syndrome (CS) cells and xeroderma pigmentosum (XP) cells (XPD, XPA, XPG, and XPF) were defective ...
