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2009 NOV 25 ... were shown to belong to the proinflammatory CD27-/CD28- population. Their potentially cytotoxic status was confirmed by staining with perforin-specific antibodies. Search for the TCR V ...
2009 NOV 24 ... a neutral red uptake assay. demonstrated that QPX produces virulence factors that are cytotoxic to M. mercenaria haemocytes. This cytotoxicity appears to be induced by clam factors, ...
2009 NOV 23 ... of hepatic CYP2B, which metabolizes cyclophosphamide into teratogenic acrolein and cytotoxic phosphoramide mustard. Moreover, PBO remarkably attenuated cyclophosphamide-induced body ...
2009 NOV 23 ... "Targeted treatment has substantially changed the field of oncology. Compared with cytotoxic chemotherapy, many novel targeted therapies are administered over long periods of time, ...
2009 NOV 23 ... mitosis. This study demonstrates that adenovirally mediated p53 overexpression at sub-cytotoxic levels enhanced the activity of low doses of cisplatin and methotrexate in HEp-2 and CAL ...
2009 NOV 24 ... to nanoparticles depositing in the brain tissues. Therefore, we investigated the cytotoxic effects of TiO2 NPs on microglia N9 cells in vitro. Results of propidium ...
2009 NOV 23 ... control mice but the tumor-infiltrating effector T cells in AdCD40L-treated mice were cytotoxic (CD107a+) in contrast to those in control-treated tumors. Furthermore, AdCD40L gene ...
2009 NOV 23 ... purification, and characterization of Affitoxin-a novel class of HER2-specific cytotoxic molecules combining HER2-specific Affibody molecule as a targeting moiety and PE38KDEL, ...
2009 NOV 23 ... material. A material that has a reduced systemic toxicity will allow higher doses of cytotoxic drugs to be delivered to the tumor with reduced side effects. Preliminary experiments ...
2009 NOV 23 ... the tumor site. Tumor growth was monitored, and 2 weeks after DC immunotherapy, the cytotoxic activity and the infiltration of CD8(+) T cells were monitored in different groups. ...
2009 NOV 23 ... progressive disease after prior surgical resections, high dose interleukin-2. and anti-cytotoxic T lymphocyte antigen-4 antibody received sequential treatments with autologous tumor ...
2009 NOV 23 ... length. After NIR triggered drug release, the released Pt compounds were observed to be cytotoxic, while remaining nanoparticles did not exhibit any cytotoxicity," wrote M.C. Tan and ...
2009 NOV 23 ... amount of 4-hydroxy-2-nonenal (FINE), which is a major lipid peroxidation product and a cytotoxic aldehyde, is increased in the human failing myocardium. This study was designed to ...
2009 NOV 23 ... Immunology Immunotherapy (Identification and modification of an HLA-A*0201-restricted cytotoxic T lymphocyte epitope from Ran antigen. Cancer Immunology Immunotherapy, ...
2009 NOV 23 ... of in-stent restenosis and late stent thrombosis is intuitively favored over the use of cytotoxic or cytostatic drugs released from a drug-eluting stent (DES). Promoting accelerated ...
2009 NOV 23 ... neuroblastoma (NB), a tumor that relapses at high rates following high-dose conventional cytotoxic therapy and autologous bone marrow cell (BMC) reconstitution. This study presents a ...
2009 NOV 23 ... Both extracts at a final concentration of 2.5, 5, 10, or 20 mg/plate exhibited only mild cytotoxic effects. The plant extracts at the concentrations of 2.5, 5 and 10 mg/plate in the ...
2009 NOV 23 ... of ADM (0.5 mu g/mL) combined with 0.1, 1, or 10 mu g/mL TRAIL had a synergistic cytotoxic effect on MCF-7 cells, which was more marked with the combination of TRAIL (0.1 mu g/mL) ...
2009 NOV 24 ... of receptors on NK cells and their subsets was analyzed by flow cytometry. The cytotoxic CD3(-)CD16(bright) NK subset constituted 78.97%, while the regulatory CD3(-)CD16(dim) NK ...
