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2009 NOV 16 ... EPCs in a mouse model of diabetes induced by streptozotocin. 2. Compared with non-diabetic controls, diabetic mice had reduced circulating EPCs (0.59 +/-0.11 vs 0.94 +/-0.21%, ... circulating EPCs (0.59 +/-0.11 vs 0.94 +/-0.21%, respectively; p<0.01) and increased plasma endothelial microparticles (18 642 +/-6809 vs 5692 +/-1862/mL, respectively; p<0.01). ...
2009 NOV 16 ... and angiotensin receptor blockade (ARB) on urinary CTGF levels in patients with non-diabetic proteinuria, and (3) a study of how proximal tubular function affects excretion and ... trials, treatment with FG-3019 was associated with an increase in levels of CTGF in the plasma, likely due to co-complex formation of CTGF with FG-3019, and appeared to reach a ...
2009 NOV 16 ... insulin resistance, or beta-cell dysfunction." "We genotyped 1495 non-diabetic subjects from Southern Germany for the five tagging single nucleotide polymorphisms ... rs10819699, consistently tended to associate with higher insulin release as derived from plasma insulin at 30 min(OGTT), AUC(C-peptide)-to-AUC(Gluc) ratio and the ...
2009 NOV 16 ... predispose to CVD. Recent reports suggested that the T/T genotype may predispose type 2 diabetic and hypertensive patients to the development of progressive renal insufficiency. The aim ... and heterozygous (C/T) genotypes. We also measured serum vitamin B-12, folate, total plasma Hcy (tHcy), lipid profile and serum albumin concentrations in the study group. Thirty ...
2009 NOV 23 ... According to recent research from the United States, "Diabetic neuropathy may be a result of disturbed vasomotion, the spontaneous rhythmic ... (3) the Hurst exponent. The rest were more traditional measures including (4) fasting plasma Glucose (FPG), (5) glycosylated hemoglobin level (HbA1c), (6) fasting insulin levels ...
2009 NOV 16 ... type 2 diabetes. ACTOplus met is not for patients with type 1 "juvenile" diabetes or diabetic ketoacidosis. ACTOplus met has not been studied in children and is not recommended for ... The secondary endpoints of the study included change from baseline in fasting plasma glucose (FPG), fasting insulin and homeostatic model assessment-insulin resistance ...
2009 NOV 23 ... as a result of enhanced insulin sensitivity during electroacupuncture in spontaneously diabetic Goto-Kakizaki rats. Metabolism - Clinical and Experimental, 2009;58(10):1372-1378). ... uptake during EA. A significant decrease in fasting blood glucose and ail increase in plasma insulin levels were observed during the fasting period in GK rats treated with EA. Blood ...
2009 NOV 23 ... aim was to investigate gender differences in endothelial function in aortas from type 2 diabetic model mice," scientists in Tokyo, Japan report. "The nonfasting plasma ...
2009 NOV 23 ... in the journal Diabetes, "The metabolic outcome of islet cell transplants in type 1 diabetic patients is variable. This retrospective analysis examines whether differences in ... were compared with outcome parameters during the first 6 posttransplant months (i.e., plasma C-peptide, glycemic variability, and gain of insulin independence). Correlations in ...
2009 NOV 16 ... events, insulin resistance, and type 2 diabetes. In this study, lean and obese diabetic ob/ob mice were submitted or not to chronic ethanol intake via the drinking water for 6 ... intake via the drinking water for 6 months, which was associated with moderate levels of plasma ethanol." "Plasma levels of alanine aminotransferase and aspartate ...
2009 NOV 23 ... We sought to assess the usefulness of the LAR as a measure of insulin resistance in non-diabetic white adults. Leptin and adiponectin levels were measured in 2,097 non-diabetic ... "As hypertrophic adipocytes secrete more leptin and less adiponectin, the plasma leptin: adiponectin ratio (LAR) has been proposed as a potentially useful measure of ...
2009 NOV 16 ... injections therapy (MDI) on glicemic control and on lipid profile in type 1 and type 2 diabetic patients. We divided the patients in two groups: in the first one (n=32) CSII was ... value was lower after 3, 6, 9, and 12 months with CSII compared to MDI. Fasting plasma glucose (FPG) value was lower with CSII after 3, 6, and 12 months compared to MDI. ...
2009 NOV 23 ... (p <0.02). Conclusions/interpretation The first-degree offspring of type 2 diabetic patients show insulin resistance and beta cell dysfunction in response to oral glucose ... During the OGTT, the offspring of individuals with type 2 diabetes showed 4-14% higher plasma glucose from 30 to 120 min (p <0.05) and 20-29% higher serum insulin from 90 to 120 ...
2009 NOV 23 ... is a frequent and severe complication of diabetes. Multiple metabolic defects in type 2 diabetic patients result in oxidative injury of dorsal root ganglia (DRG) neurons," scientists ... fed a control (10% kcal %fat) or high-fat (45% kcal %fat) diet to explore the impact of plasma lipids on the development of neuropathy. We also examined oxidized lipid-mediated injury ...
2009 NOV 23 ... that impaired metabolism of these elements may contribute to the progression of DM and diabetic complications." Viktorinova and colleagues published their study in ... (Cu), zinc (Zn), and magnesium (Mg). The aim of the present study was to investigate plasma levels of these elements in patients with DM and in healthy Subjects," researchers in ...
2009 NOV 23 ... the efficacy of TCM on insulin sensitivity and other related metabolic factors in type 2 diabetic patients. There were 43 newly diagnosed type 2 diabetic patients enrolled in this study, ... groups, administrated with TCM and placebo, respectively. Glucose disposal rate, fasting plasma glucose, postprandial plasma glucose, glycated hemoglobin, and other metabolic ...
2009 NOV 23 ... values were calculated from the mean plasma glucose levels. Two hundred and two type 2 diabetic patients without CLD were studied as controls. Although GA was strongly correlated with ...
2009 NOV 23 ... effects of MTHFR gene mutation and consequent hyperhomocysteinemia on the development of diabetic microvascular complications in comparison with the other defined risk factors. Diabetic ... A point mutation (677 C-T) of MTHFR gene results in a significant increase at plasma homocysteine levels," scientists writing in the journal Endocrine report. ...
2009 NOV 16 ... concentrations of bone metabolism markers in type 1 diabetes mellitus patients and non-diabetic and to evaluate the influence of periodontitis on biomarkers of bone formation in these ... study, investigators in Glasgow, the United Kingdom conducted a study "To determine plasma concentrations of bone metabolism markers in type 1 diabetes mellitus patients and ...
