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2009 NOV 23 ... and bipolar disorder, has high affinity for serotonergic, alpha-adrenergic, and dopaminergic receptors, suggesting potential for antipsychotic and cognitive-enhancing properties. ...
2009 NOV 23 ... "Glial-cell-line-derived neurotrophic factor (GDNF) is a potent survival factor for dopaminergic neurons, and hence serves as a therapeutic candidate for the treatment of Parkinson's ...
2009 NOV 23 ... "The canonical histopathological feature of Parkinson's disease (PD) is the loss of dopaminergic neurons in the ventral midbrain. Although the common sporadic/idiopathic form of PD most ...
2009 NOV 23 ... of microglia may contribute to the neuronal damage seen in the nigro-striatal dopaminergic system of PD patients," scientists in the United States report. ...
2009 NOV 23 ... does not lead to mitochondrial complex I inhibition as seen in males and the progressive dopaminergic cell loss in substantia nigra (SNpc) is significantly attenuated. Redox driven apoptotic ...
2009 NOV 17 ... that are updated based on prediction errors, and processing of these errors involves dopaminergic neuromodulation in the striatum." "To test the hypothesis that the COMT ...
2009 NOV 23 ... Genetics, Selegiline, Antidyskinetic, Antiparkinson, Central Nervous System Agent, Dopaminergic, Neuroprotective Agent, Neurotoxins. This article was prepared by Pain & ...
2009 NOV 23 ... and its synthesizing enzyme glutamic acid decarboxylase. We have found no evidence for a dopaminergic phenotype. Subgroups of NT2 neurons respond to the application of nitric oxide donors ...
2009 NOV 23 ... (KGDH) was completely abolished upon increasing levels of MAO-B activity in a dopaminergic cell model system (Kumar et al., J Biol Chem 278:46432-46439, 2003). MAO-B mediated ...
2009 NOV 23 ... play a crucial physiological role in the mammalian brain as an endogenous regulator of dopaminergic activity," investigators in Krakow, Poland report. "It is well known that ...
2009 NOV 23 ... So far, there has been no study specifically investigating the influence of diurnal dopaminergic medication (DM) on nocturnal slow wave sleep (SWS)." "Polysomnographic ...
2009 NOV 23 ... Journal of Proteome Research, "Parkinson's disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra and formation of intracytoplasmic Lewy bodies (LBs). ...
2009 NOV 16 ... in kinase, COR or LRR domains, resp.). Ectopic expression of WT or mutant LRRK2 in dopaminergic neurons caused their significant loss accompanied by complex age-dependent changes in ...
2009 NOV 23 ... A new study, 'Effect of microglia activation on dopaminergic neuronal injury induced by manganese, and its possible mechanism,' is now available. ...
2009 NOV 23 ... polymerization to form neuromelanin, since normal individuals have this pigment in their dopaminergic neurons in the substantia nigra. The neurons lost in individuals with Parkinson's ...
2009 NOV 16 ... reported to respond differentially to fluctuating basal levels of glucocorticoids, with dopaminergic responses in the core of the NAc being somewhat impervious to fluctuating levels of ...
2009 NOV 16 ... The researchers concluded: "Progression of motor signs predominantly mediated by non-dopaminergic systems may be a useful preclinical marker for incident apathy in PD." ...
2009 NOV 16 ... a study from Dresden, Germany, "Interleukin-1 (IL-1) plays a pivotal role in terminal dopaminergic differentiation of midbrain-derived neural precursor cells already committed to the ...
