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2009 NOV 16 ... and inducible activation in JAK2. Two of the mutants, K539I and N622I, resulted in erythrocytosis in mice. Scanning mutagenesis of the SH2-pseudokinase domain linker indicated that its ...
2009 MAY 25 ... Investigators publish new data in the report 'The complete evaluation of erythrocytosis: congenital and acquired.' According to recent research from the United States, ...
2009 MAR 30 ... of adaptation to hypoxia in high-altitude (HA) dwellers. Chronic hypoxemia, excessive erythrocytosis and frequently pulmonary hypertension (PH), which may lead to cardiac failure, develop ...
2009 JUN 15 ... there was no difference regarding the prevalence of hypertension, but there was more erythrocytosis among the ADPKD group. The incidence of posttransplantation diabetes mellitus was ...
2009 JUL 27 ... is a hallmark of PV. We therefore hypothesized that NF-E2 overexpression contributes to erythrocytosis, the pathognomonic feature of PV. Consequently, we investigated the effect of NF-E2 ...
2009 AUG 31 ... exons 12 and 14 mutations have been detected in V617F-negative patients with idiopathic erythrocytosis," scientists in Greece report. "The need for a rapid and accurate assay ...
2009 JUL 6 ... According to recent research from Cairo, Egypt, "Erythrocytosis is relatively common following kidney transplantation. It increases the risk of ...
2009 JUN 1 ... and allowing it to activate the EPO gene. We previously identified and characterized an erythrocytosis-associated HIF2A mutation, G537W. More recently, we reported two additional...
2009 NOV 2 ... "While anemia is common in patients on chronic hemodialysis (HD), spontaneous erythrocytosis is rare and can be caused by either the same conditions causing...
2009 NOV 9 ... on outcomes in renal transplant recipients without proteinuria or posttransplantation erythrocytosis. Fifty renal transplant recipients (30 men and 20 women, with a mean [SD] age of 40 [13] ...
2009 AUG 10 ... of low allele burden of JAK2 exon 12 mutations using TA-cloning in patients with erythrocytosis.' "Polycythemia vera (PV) is a clonal myeloproliferative neoplasia associated with the ...
2009 APR 21 ... if their hemoglobin alleles confer high oxygen affinity, predicted to result in chronic erythrocytosis at low elevation," wrote K.G. Mccracken and colleagues, University of Alaska.
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2009 NOV 16 ... mutations have been identified in V617F negative polycythaemia vera (PV) or idiopathic erythrocytosis (IE) patients. The patients present with...
2009 FEB 23 ... oxygen affinity, the decrease in the liberation of the oxygen determines a secondary erythrocytosis," investigators in Madrid, Spain report.
"In this work, we present ...
2009 MAY 4 ... the report, 'Erythropoietin production by a hepatic adenoma in a patient with severe erythrocytosis,' have been published. According to recent research from Norway, "A 53-year-old ...
2009 APR 20 ... we performed molecular screening in 409 patients with polycythemia vera or unclear erythrocytosis with un-mutated JAK2V617. The frequency of JAK2exon12 mutations was 10/63 (15.9%) in PV ...
2009 NOV 2 ... 3 normal Volunteers had recombinant human erythropoietin (rhEpo) administered until mild erythrocytosis occurred, then were studied upon rhEpo withdrawal. Neocytolysis ensued that most evident ...
2009 JUL 27 ... V, Gonzales-Castaneda C. High serum testosterone levels are associated with excessive erythrocytosis of chronic mountain sickness in men. Am J Physiol Endocrinol Metab 296: E1319-E1325, ...