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2009 SEP 21 ... ischemia and reperfusion injury in offspring in a sex-dependent manner, which was due to fetal programming of PKC epsilon gene repression resulting in a down-regulation of PKC epsilon function in ...
2009 NOV 18 ... and low sperm counts may comprise a testicular dysgenesis syndrome (TDS), resulting from fetal testis dysfunction during a critical developmental period involving reduced androgen ... anogenital distance (AGD) as a measure of androgen action within the masculinization programming window. Intratesticular testosterone and steroidogenic enzyme gene expression were ...
2009 OCT 5 ... recent research published in the journal Brain, Behavior, and Immunity, "The concept of fetal programming states that changes in the fetal environment during sensitive periods of organ ...
2009 OCT 12 ... gestation was an important early origin of adult cardiac and metabolic disorders due to fetal programming that permanently shaped the body's structure, function, and metabolism and contributed ...
2009 JUL 20 ... androgen receptor (AR) and progesterone receptor (PGR) proteins were determined at fetal (days 90 and 140), postpubertal (110 months), and adult (21 months; only prenatal ... Ortega and colleagues published their study in Reproduction (Developmental programming: prenatal androgen excess disrupts ovarian steroid receptor balance. Reproduction, ...
2009 NOV 4 ... "The associated alterations in yolk leptin deposition as well as in yolk-sac membrane, fetal hypothalamus and muscle gene expression may be involved in mediating such programming ...
2009 JUL 20 ... obesity, insulin resistance, and markers of inflammation, supporting the concept of fetal programming." "Fifty-three lean and 68 obese women with singleton term pregnancies ...
2009 NOV 2 ... and cognitive problems have been reported, with different relations for boys and girls. Fetal programming hypotheses underline these associations and state that the early development of the ...
2009 SEP 7 ... Fresh data on fetal growth retardation are presented in the report 'Markers of insulin sensitivity in ... for adiponectin and IL-6 in particular, and suggesting a role for the placenta in the programming of these hormones." Street and colleagues published their study in ...
2009 NOV 24 ... chromatin modifications and non-coding RNAs) and reported evidence for their role in fetal programming were briefly reviewed. The development of the vascular system is strongly influenced by ...
2009 JUL 13 ... According to a study from Rotterdam, Netherlands, "Fetal malnutrition may predispose to type 2 diabetes through gene programming and ...
2009 AUG 17 ... them, prenatal stress (i.e. stress experienced by the pregnant mother with impact on the fetal ontogeny) has clear programming effects on the cardiovascular system," scientists in ...
2009 JUL 21 ... According to recent research from Adelaide, Australia, "Fetal adaptations to periods of substrate deprivation can result in the programming of glucose ...
2009 AUG 3 ... According to a study from Nice, France, "Fetal exposure to environmental estrogens may contribute to hypofertility and/or to testicular ... low doses and with a high affinity for this GPCR, could interfere with the developmental programming of fetal germ cell proliferation and/or differentiation when they cross the placenta." ...
2009 SEP 28 ... the mechanism(s) by which lead-induced toxicity occurs remains unknown. Epigenetic fetal programming via DNA methylation may provide a pathway by which environmental lead exposure can ...
2009 AUG 3 ... the United States, "A sub-optimal intrauterine environment alters the trajectory of fetal development with profound effects on life-time health. Altered methylation, a proposed ... a potential epigenetic mechanism whereby reduced maternal nutrition has long-term programming effects on fetal organ development." Unterberger and colleagues published ...
2009 JUL 13 ... intrauterine programming or two phenotypes of one genotype." "The fetal insulin hypothesis proposes that common genetic variants that reduce insulin secretion ...
2009 NOV 9 ... and disease hypothesis investigates the potential association between a compromised fetal and postnatal environment and later disease, such as obesity and type 2 diabetes, in the ... Investigators publish new data in the report 'Early programming of adipose tissue function: a large-animal perspective.' According to a study from ...
2009 JUL 27 ... Great impact is attached to the intrauterine period and the lifelong implications of fetal programming," wrote A. Kautzky-Willer and colleagues, Medical University of Vienna, Division of ...
2009 NOV 2 ... Psychology. The researchers concluded: "Data are compatible with adverse fetal 'programming' by overexposure to glucocorticoids and caution against excessive intake ...
