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2009 DEC 1 ... may be required. A carboxin resistance allele of the Coprinopsis cinerea sdi1 gene, encoding the iron-sulphur protein subunit of succinate dehydrogenase, was developed by ... subunit of succinate dehydrogenase, was developed by introducing a suitable point mutation in the histidine block responsible for binding of the associated iron ion." ...
2009 DEC 1 ... microsatellite markers. Mutation analysis was done by direct sequencing of the candidate gene GRK1 located in the region. The segregation of a novel mutation in the family and the ...
2009 DEC 1 ... stigma exsertion, our results demonstrate that the S-locus receptor kinase (SRK) gene further enhances pistil elongation and stigma exsertion in this mutant background, a ... we performed screens for mutants exhibiting a modified SI response." "A mutation in the RNA-dependent RNA polymerase RDR6, which functions in trans-acting short ...
2009 DEC 1 ... only during seed development. OLEOSIN promoter is a very useful tool for seed-specific gene engineering and seed bioreactor designing," scientists in Beijing, People's Republic ... bound to two conserved RY elements in this region. In transient expression assays, mutation in either RY element dramatically reduced LEC2 activation of OLEOSIN promoter activity, ...
2009 DEC 1 ... cell death of flu seedlings. One of the soldat mutations, soldat10, affects a gene encoding a plastid-localized protein related to the human mitochondrial transcription ... the human mitochondrial transcription termination factor mTERF. As a consequence of this mutation, plastid-specific rRNA levels decrease and protein synthesis in plastids of soldat10 is ...
2009 DEC 1 ... an extra-adrenal tumor before the age of 45, and SDHC could be the responsible gene in cases developing a single head and neck tumor, independently of age," wrote A. ... the absence of familial antecedents of the disease does not preclude the existence of a mutation affecting any of the five major susceptibility genes." "In fact, 11-24% ...
2009 DEC 2 ... (RGCs), resulting in irreversible loss of vision. Although members of the neurotrophin gene family in various species are known to support the survival of numerous neuronal ... kinase receptor B (TrkB). Expression of recombinant NT-4 carrying the most frequent mutation was demonstrated to lead to decreased activation of TrkB," wrote F. Pasutto and ...
2009 DEC 1 ... concluded: "These results indicate that GL2 directly regulates cell wall-related gene expression during root development." Tominagawada and colleagues published ... mutants in Arabidopsis." "Among several root hair mutants, only the gl2 mutation affected root cell wall polysaccharides. Five of the 10 genes encoding cellulose ...
2009 NOV 30 ... "The Corynebacterium glutamicum NCgl2281. gene encodes an RNase E/G family endoribonuclease having an additional N-terminal domain of ... "Both FL- and Delta N-NCgl2281 rescued the defects caused by the rng::cat mutation, i.e., accumulation of 16S rRNA precursor, overproduction of the AdhE protein, and ...
2009 NOV 30 ... with hemophilia A. Predictors of ITI outcome are still debated, and the role of F8 gene mutations in this is not well established. To investigate the relationship between F8 ... 1.7, 95% confidence interval (CI) 1.1-2.1, P = 0.01]. On multivariate analysis, the mutation risk class remained a significant predictor of success [adjusted odds ratio (OR) 6.2, ...
2009 DEC 1 ... United Kingdom, "The transcriptional regulation of the LATE ELONGATED HYPOCOTYL (LHY) gene is key to the structure of the circadian oscillator, integrating information from ... that two classes of protein complexes interact with a G-box and with novel 5A motifs; mutation of these sites reduced the amplitude of oscillation and broadened the peak of ...
2009 NOV 30 ... general response to photoreceptor injury. Independent of the nature of the toxic insult (gene mutation, light), LIF may activate an endogenous rescue pathway that protects viable ...
2009 DEC 1 ... biotic defense responses, including elevated levels of salicylic acid, camalexin, PR gene expression, and resistance to the bacterial pathogen Pseudomonas syringae. PROTEIN ... in Freiburg, Germany report. "Here, we report that the mkp1 null mutation in the Columbia (Col) accession results in growth defects and constitutive biotic ...
2009 NOV 30 ... studies. A genetically distinct but similar disorder, caused by mutations of the gene SPRED1 was recently identified (and recently named Legius syndrome). The authors write ... family member who seeks medical attention for a genetic disorder) carrying a SPRED1 mutation identified through clinical testing, who participated with their families in a ...
2009 NOV 30 ... other countries, the Korean strains had more than 99% sequence homology with those in gene and protein. Based on our sequence analysis of VP19 and VP28 of WSSV from various shrimp ... implies that a single genetic strain of WSSV has been circulating in Korea and that its mutation rate is very low. In comparison with known sequences of VP19 and VP28 genes of WSSV ...
2009 NOV 30 ... a mutation in the homolog of a 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase gene found in plants. The vte3 npq1 lor1 triple mutant with beta-to-copherol survived better ...
2009 NOV 30 ... sequencing of the coding region of the tumor-associated calcium signal transducer 2 gene (TACSTD2) in DNA from the two brothers and their relatives." "Laser ... OCT were performed on the left cornea of the younger brother. We report a novel in-frame mutation of TACSTD2, c. 526_576del 51, in the two brothers with GDLD. The identified molecular ...
2009 NOV 30 ... supported by point mutations and duplication and triplication of the alpha-synuclein gene (SNCA) that are causative of these disorders." "The middle hydrophobic ... only the rate of fibril formation, without abrogating filament assembly. Further, mutation of residue E83 to an A rescued the ability of mutant Delta 76-77 alpha-synuclein to ...
2009 DEC 1 ... For additional information, contact S. Hake, Dept. of Agriculture ARS, Center Plant Gene Express, Albany, CA 94710, USA. Publisher contact information for the ... being consumed in the production of an ovule." "The bearded-ear (bde) mutation affects floral development differently in the upper and lower meristem. The upper floral ...
2009 DEC 1 ... multinucleate syncytia. This study shows that it is allelic with the proline-tRNA(CGG) gene SPATRNAPRO.02." "Its nucleotide sequence contains a C -> T ... research from Debrecen, Hungary, "spl1-1 was originally identified as a spontaneous mutation genetically interacting with sep1-1 and cdc4-8 in producing multinucleate syncytia. This ...
