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2009 SEP 7 ... study in Molecules and Cells (H19 gene is epigenetically stable in mouse multipotent germline stem cells. Molecules and Cells, 2009;27(6):635-640). For more information, contact ...
2009 NOV 3 ... Epiblast identity and pluripotency were confirmed by contribution to chimaeras with germline transmission. These observations indicate that segregation of hypoblast from the ... "Embryonic stem (ES) cells can be derived and propagated from multiple strains of mouse and rat through ...
2009 NOV 10 ... haploid ES cells, even after genetic engineering, generated viable offspring capable of germline transmission. Hence, haploid medaka ES cells stably maintain normal growth, ... According to recent research published in the journal Science, "Haploid embryonic stem (ES) cells combine haploidy and pluripotency, enabling direct genetic analyses of ...
2009 SEP 28 ... to postembryonic development. Third, sexual reproduction of M. lignano allowed to follow germline formation during postembryonic development, regeneration, and starvation. Fourth, piwi ... Scientists discuss in 'Stemcells are differentially regulated during development, regeneration and homeostasis in ...
2009 SEP 14 ... niche signals and intrinsic factors in a variety of systems. Drosophila ovarian germline stem cells (GSCs) have been one of the most productive systems for identifying the factors ...
2009 SEP 14 ... from testicular cells. Although pluripotent stem cells have been obtained from defined germline stem cells (GSCs) of mouse neonatal testis, only multipotent stem cells have been obtained so far ...
2009 NOV 2 ... Ectopically expressing the differentiation factor bag-of-marbles (Bam) removes germline stem cells from the niche. However, withdrawing ectopic Bam causes interconnected spermatogonia. to ...
2009 OCT 27 ... we establish that while the tumor often contains at least one apparently bona fide germlinestem cell, the majority of cells exhibit an intermediate fate between a stem cell and ...
2009 SEP 14 ... we have developed a TAp63 conditional knockout mouse and used it to ablate TAp63 in the germline (TAp63(-/-)) or in K14-expressing cells in the basal layer of the epidermis ... United States, "The cellular mechanisms that regulate the maintenance of adult tissue stem cells are still largely unknown. We show here that the p53 family member, TAp63, is ...
2009 OCT 12 ... new data in stem cell research. According to recent research from the United States, "Germline stem cells (GSCs) in Drosophila are descendants of primordial germ cells (PGCs) specified during ...
2009 OCT 26 ... apical region of the Drosophila testis contains a niche with two stem cell populations: germline stem cells (GSCs) and cyst progenitor cells (CPCs). Asymmetrical division of these stem cells leads ...
2009 OCT 12 ... Data detailed in 'Early lineage specification of long-lived germline precursors in the colonial ascidian Botryllus schlosseri' have been presented. "In ... specification, and we are interested in both the origins and the persistence of stemcells responsible for asexual development in colonial ascidians. In this study, we ...
2009 AUG 31 ... study in Biology of Reproduction (Abnormal DNA Methyltransferase Expression in Mouse Germline Stem Cells Results in Spermatogenic Defects. Biology of Reproduction, 2009;81(1):155-164). ...
2009 NOV 2 ... data in the report 'The glypican Dally is required in the niche for the maintenance of germline stem cells and short-range BMP signaling in the Drosophila ovary.' "The Drosophila ovary is an ...
2009 NOV 2 ... specifically in the somatic stem cells, preventing them from displacing neighboring germline stem cells in a manner that depends on the adhesion protein integrin," wrote M. Issigonis and ...
2009 AUG 17 ... According to recent research from Odense, Denmark, "Cancer-germline antigens are promising targets for cancer immunotherapy, but whether such therapies will ... cancer immunotherapy, but whether such therapies will also eliminate the primary tumor stem cell population remains undetermined. We previously showed that long-term cultures of ... showed that long-term cultures of telomerized adult human bone marrow mesenchymal stem cells can spontaneously evolve into tumor-initiating, mescnchymal stem cells (hMSC-TERT20), ...
2009 AUG 10 ... "Soma-germline interactions control fertility at many levels, including stem cell proliferation, ... (meiotic maturation) and to promote contraction of the follicle-like gonadal sheath cells that surround oocytes," scientists in the United States report. "Using ...
2009 NOV 16 ... in less developed vertebrates, pluripotent stemcells can be generated from the female germline even in mammals, via parthenogenetic activation of oocytes. Recently, testis-derived ...
2009 AUG 24 ... mice after stable genetic modification. These NOD ES cell lines also show efficient germline transmission, with offspring developing diabetes," wrote J. Nichols and colleagues, ... putative disease loci via gene targeting has been hampered by the lack of NOD embryonic stem (ES) cells. We describe here the derivation of NOD ES cell lines capable of generating ...
2009 SEP 22 ... p53 protein levels enabled fibroblasts to give rise to iPS cells capable of generating germline-transmitting chimaeric mice using only Oct4 ( also known as Pou5f1) and Sox2. ... "Reprogramming somatic cells to induced pluripotent stem (iPS) cells has been accomplished by expressing pluripotency factors and oncogenes(1-8), ...
