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Search Results for Gleevec


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2009 Lasker Awards Honor Trailblazers in Medical Research and Public Service:
2009 SEP 28 ... Cancer Center. Druker and Lydon's research led to the development of imatinib (or Gleevec). Sawyers' research spearheaded efforts toward combating the resistance to...
Subject: The Albert and Mary Lasker Foundation
Price: $3.00
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ARIAD Announces Preliminary Results from Ongoing Clinical Trial of Its Investigational, Bcr-Abl Inhibitor – AP24534 – in Drug-Resistant Chronic Myeloid Leukemia
2009 AUG 10 ... drug-resistant cases of CML and Ph+ ALL. First-generation therapies, such as imatinib (Gleevec®), and second-generation therapies, such as dasatinib (Sprycel®) and nilotinib ...
Subject: ARIAD Pharmaceuticals, Inc.
Price: $3.00
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ARIAD's AP24534 Featured in Cancer Cell Publication as a Potential First-in-Class Pan BCR-ABL Inhibitor
2009 NOV 16 ... specific mutations that confer clinical resistance to marketed CML therapies imatinib (Gleevec®), dasatinib (Sprycel®), and nilotinib (Tasigna®). "We ...
Subject: ARIAD Pharmaceuticals
Price: $3.00
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Drug could provide first treatment for scleroderma
2009 NOV 2 ... have identified a drug that is currently approved to treat certain types of cancer, Gleevec, that could provide the first treatment for scleroderma, a chronic connective tissue ...
Subject: Hospital for Special Surgery
Price: $3.00
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Janet Rowley, MD, a Researcher Funded by the Leukemia & Lymphoma Society, Receives Presidential Medal of Freedom
2009 AUG 10 ... of two chromosomes. Her discovery was a key step in the eventual discovery of Gleevec, a targeted therapy for CML patients. Rowley, 84, is the Blum-Riese ...
Subject: Leukemia
Price: $3.00
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New schwannoma study findings reported from University of Toronto
2009 AUG 17 ... by multiple schwannomas, underlying the need for biological targeted therapies. Gleevec (STI571, imatinib mesylate), in addition to the bcr-abl oncogene in chronic myelogenous ...
Subject: Schwannoma
Price: $3.00
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New treatment more than doubles survival for high risk childhood leukemia
2009 OCT 19 ... in the appropriate use of expensive medications." Known commercially as Gleevec®, imatinib is a pill that's used to treat some adult leukemias and ...
Subject: Child & Family Research Institute
Price: $3.00
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Novartis drug Tasigna meets primary endpoint in pivotal trial against Gleevec as first-line treatment in chronic myeloid leukemia patients
2009 NOV 2 ... endpoint in the first head-to-head comparison with the company's groundbreaking drug Gleevec® (imatinib mesylate) tablets*. Tasigna produced faster and deeper responses than ...
Subject: Novartis
Price: $3.00
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Novartis drug Tasigna(R) meets primary endpoint in pivotal trial against Gleevec(R) as first-line treatment in chronic myeloid leukemia patients
2009 NOV 2 ... endpoint in the first head-to-head comparison with the company's groundbreaking drug Gleevec=AE (imatinib mesylate) tablets*. Tasigna produced faster and deeper responses than...
Subject: Chronic Myeloid Leukemia
Price: $3.00
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Research conducted at University of Minnesota has provided new information about breast cancer
2009 OCT 19 ... kinase inhibitor dasatinib (Sprycel; BMS-354825) is approved for use in imatinib (Gleevec; STI 571)resistant or-intolerant chronic myelogenous leukemia and may be useful for ...
Subject: Breast Cancer
Price: $3.00
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Research from Harvard University reveals new findings on merkel cell cancer
2009 AUG 31 ... (IHC) in part prompted the initiation of a phase 2 clinical trial of imatinib mesylate (Gleevec, Novartis Pharmaceuticals, East Hanover, NJ) for the treatment of advanced MCC," ...
Subject: Merkel Cell Cancer
Price: $3.00
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Research from S. Cooper and co-authors reveals new findings on leukemia therapy
2009 NOV 23 ... leads to the fusion-protein BCR-ABL. Prior to the development of imatinib mesylate (Gleevec), treatment was limited and provided only limited survival benefit," researchers in the ...
Subject: Leukemia Therapy
Price: $3.00
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Research from University of Pittsburgh, Pittsburgh Cancer Institute has provided new information about pharmacokinetics
2009 SEP 21 ... the pharmacokinetics of imatinib,' new data in pharmacokinetics. "Imatinib mesylate (Gleevec/Glivec), which has revolutionized the treatment of chronic myeloid leukemias (CML) and ...
Subject: Pharmacokinetics
Price: $3.00
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Research on hematopoietic reported by M. Xaymardan et al
2009 NOV 16 ... of the clusters could be completely blocked by adding a c-kit/tyrosine kinase inhibitor, Gleevec (imatinib mesylate; Novartis International, Basel, Switzerland, ...
Subject: Hematopoietic
Price: $3.00
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Research results from University of Groningen, Department of Pathology update understanding of leukemia therapy
2009 AUG 24 ... CD33+ CML cells when treatment was combined with the Bcr-Abl tyrosine kinase inhibitor, Gleevec. Importantly, ex vivo treatment of patient-derived CD33+ AML tumor cells with ...
Subject: Leukemia Therapy
Price: $3.00
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Researchers at University of Oklahoma release new data on leukemia
2009 SEP 28 ... A report, 'Tumor lysis syndrome after starting treatment with Gleevec in a patient with chronic myelogenous leukemia,' is newly published data in Journal of ...
Subject: Leukemia
Price: $3.00
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Scientists at University of Texas describe research in bronchiolitis
2009 OCT 19 ... associated with chronic fibrosing diseases and may potentially be treated with imatinib (Gleevec), a c-KIT blocker," scientists in the United States report. ...
Subject: Bronchiolitis
Price: $3.00
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Stakeholder Insight: Acute Leukemias - Reaching the Limits of Cytotoxic Chemotherapy
2009 NOV 9 ... for AML but are expected to have minimal impact on patient outcomes. Gleevec (imatinib; Novartis) is the only molecular targeted therapy used extensively in the ...
Subject: Research and Markets
Price: $3.00
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Studies from University of Kentucky, Medical Department reveal new findings on cancer
2009 AUG 3 ... "This study will determine whether MTT assays accurately assess the effect of STI571 (Gleevec; Abl kinase inhibitor) on the viability of cancer cells containing highly active Abl ...
Subject: Cancer
Price: $3.00
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Studies from University of Texas provide new data on chronic myeloid leukemia
2009 NOV 9 ... diagnosed patients with chronic myeloid leukemia (CML). The Rationale and Insight for Gleevec High-Dose Therapy (RIGHT) trial is a multicenter study of imatinib 400 mg twice a day as ...
Subject: Chronic Myeloid Leukemia
Price: $3.00
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