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2009 NOV 23 ... Tepap transcript levels were observed when the fungus was grown in medium containing glucose and the protein hydrolysate casitone. Interestingly, both the induction profile and ... the filamentous fungus Talaromyces emersonii were screened for intracellular peptidase production. Five distinct proteolytic activities with specificity for the p-nitroanilide (pNA) ...
2009 NOV 23 ... studies of the regulation of insulin biosynthesis that highlighted the key role of glucose. In addition, the C-peptide, the polypeptide that joins the A and B chains in proinsulin ... published their study in Diabetes Obesity & Metabolism (A brief perspective on insulin production. Diabetes Obesity & Metabolism, 2009;11(Suppl. 4):189-196). For additional ...
2009 NOV 23 ... onset of albuminuria and maintained the peritubular vasculature without affecting blood glucose levels, body weight or glomerular macrophage infiltration. Conclusions/interpretation We ... on alternate days from 4 to 6 months of age. Immunostaining localised renal CXCL12 production to glomerular podocytes in db/db mice with early or advanced diabetic nephropathy. ...
2009 NOV 23 ... significant insulin resistance, whereas the same length of exposure to a high level of glucose (33mM) did not cause obvious insulin resistance. Furthermore, our results showed that ... insulin resistance. Insulin resistance was accompanied by decreased mitochondrial production as evaluated by mitochondrial DNA and levels of transcripts and proteins of ...
2009 NOV 23 ... destruction of beta-cells in type 1 diabetes results in a loss of insulin production and glucose homeostasis. As such, an immense interest exists for the development of therapies ...
2009 NOV 25 ... "Recently, specific immunohistochemical markers such as erythrocyte type glucose transporter protein 1 (GLUT-1) have been described to differentiate haemangiomas and ... Journal of Oral and Maxillofacial Surgery is: Churchill Livingstone, Journal Production Dept., Robert Stevenson House, 1-3 Baxters Place, Leith Walk, Edinburgh EH1 3AF, ...
2009 NOV 17 ... obtained from C. flavus strain AL(51) was established (55.1 % mannose, 26.1 % glucose, 9.60 % xylose, 1.90 % galactose)," wrote K. Pavlova and colleagues. The ... Pavlova and colleagues published their study in Folia Microbiologica (Production of an exopolysaccharide by Antarctic yeast. Folia Microbiologica, 2009;54(4):343-348). ...
2009 NOV 23 ... cultures were used to characterize the metabolism of cultures surviving after glucose depletion." "Survival of stationary-phase cultures in glucose-depleted ... (ammonia) accumulated throughout long-term stationary phase (12 weeks). Acid and ammonia production was balanced so that the culture pH was maintained above pH 5.6. Strains isolated from ...
2009 NOV 24 ... and the aciduricity of this bacterium. When cultures were supplemented with glucose, the glycolytic rate of a VicK null mutant was significantly decreased compared to the ... "The regulation of acid production in and the tolerance to low pH of the cariogenic bacterium Streptococcus mutans have ...
2009 NOV 16 ... free fatty acid concentrations by insulin was dramatically improved. Basal hepatic glucose production was unchanged by rgAd110-244 infusion. This acute rgAd110-244 treatment improved glucose ...
2009 NOV 23 ... in insulin signalling and sensitivity, as measured by insulin tolerance test and glucose clamp. Conversely, while aspirin reversed the increased phosphorylation of I kappa B ... 80 mg/kg body weight) were administered to diet-induced obese rats or mice and iNOS production and insulin signalling were investigated. S-nitrosylation of IR beta/IRS-1 and Akt was ...
2009 NOV 23 ... major adaptive behaviours are positively regulated by several extrinsic factors, such as glucose, GLP-1, insulin and growth hormones (GH). Still unclear, however, it is how beta-cells ... Obesity & Metabolism (beta-Cells at the crossroads: choosing between insulin granule production and proliferation. Diabetes Obesity & Metabolism, 2009;11(Suppl. 4):54-64). ...
2009 NOV 17 ... to a study from Brisbane, Australia, "Ex vivo two-cell mouse embryos deprived of glucose in vitro can develop to blastocysts by increasing their pyruvate consumption; however, ... deprivation, indicative of peroxisomal proliferation. Reactive oxygen species (ROS) production and relationship to PPARA expression were also analysed. in glucose-deprived zygotes, ...
2009 NOV 23 ... (STZ). In cultured adult rat cardiomyocytes, apoptosis was induced by high glucose. The results showed a mouse model of STZ-induced diabetes, 7 days of ... to diabetic cardiomyopathy. The present study was to investigate the role of Rac1 in ROS production and cardiomyocyte apoptosis during hyperglycemia." "Mice with ...
2009 NOV 23 ... diet (42% calories from fat and 0.05% cholesterol) become dyslipidemic, insulin and glucose intolerant, and obese. Four groups of mice (standard diet, Western, and Western plus 1% ... in a manner resembling insulin We evaluated whether naringenin regulates lipoprotein production and insulin sensitivity in the context of insulin resistance in vivo. LDL receptor-null ...
2009 NOV 16 ... vivo fitness.' "The enzyme phosphoglucomutase (Pgm) catalyses the interconversion of glucose 1-phosphate and glucose 6-phosphate and contributes to glycolysis and the generation of ... (Pgm) is required by Salmonella enterica serovar Typhimurium for O-antigen production, resistance to antimicrobial peptides and in vivo fitness.' "The enzyme ...
2009 NOV 24 ... Research. "Increased bioenergetics demand can stimulate compensatory increases in glucose metabolism. We previously reported that neural cells expressing the brain uncoupling ... "The switch from oxidative toward glycolytic metabolism reduces the production of toxic reactive oxygen species (ROS) and increases cellular resistance to toxicity ...
2009 NOV 16 ... versus T2DM and mCON). Insulin-mediated whole-body glucose disposal (M) and endogenous glucose production (iEGP) were assessed during euglycemic-hyperinsulinemic clamps. Individuals with T2DM ...
2009 NOV 23 ... "They are also impaired in producing pyrroloquinoline quinone (PQQ) or glucose dehydrogenase (GDH). Complementation of MH15 and MH16 with cosmid clones of CP465 and ... and CP104 from an HX2 DNA library restored the antibiosis, biocontrol, and PQQ or GDH production phenotypes. A 6.7-kb BamHI fragment from CP465 that fully restored the MH15-affected ...
2009 NOV 24 ... CAT-1 (hCAT-1) and hCAT-2B. Exposure of HUVEC to high extracellular concentrations of D-glucose increases L-arginine transport, hCAT-1 mRNA expression and eNOS activity. These ... mRNA expression and eNOS activity. These phenomena are also related with increased production of reactive oxygen species (ROS), thus supporting the possibility that changes in ...
