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2009 OCT 13 ... parasites. This system is absent in humans, being replaced with glutathione and glutathione reductase, and as such offers a target for selective inhibition." "As part of a ...
2009 OCT 19 ... strokes. The proteins encoded by the methylenetetrahydrofolate reductase (MTHFR) and glutathione S-transferase omega-1 (GSTO-1) genes are, through oxidative mechanisms, key participants ...
2009 NOV 23 ... constitutive expression of enzymes involved in cellular redox maintenance, such as glutathione reductase, thioredoxin, and thioredoxin reductase is observed in female brain. Exposure to MPTP ...
2009 NOV 1 ... and Se-supplemented (0.2 or 2 mu g Se/g diet) rats, but the activities of liver glutathione peroxidase and thioredoxin reductase and concentration of liver Se were significantly ...
2009 NOV 23 ... +/- 13.44 ) years." "ACP1 genotype was found to directly correlate to glutathione reductase activity (P < .001) and levels of low-density lipoprotein cholesterol (P = .038). ...
2009 NOV 16 ... could be mediated via induction of detoxifying enzymes, including quinone reductase and glutathione transferase," researchers in Riyadh, Saudi Arabia report. "This study was ...
2009 NOV 16 ... high training loads have on athletes' redox status, superoxide dismutase (SOD), glutathione reductase, glutathione peroxidase (GPx), and creatine kinase activities; total antioxidant status ...
2009 NOV 1 ... and protein carbonyl production, antioxidant enzymes glutathione peroxidase (GPx), and glutathione reductase (GR) activities were measured. No significant difference in nutritional status or ...
2009 NOV 23 ... analyses of activities of superoxide dismutase (SOD), glutathione peroxidase (GPx) and glutathione reductase (GRx); also, glutathione status, including reduced glutathione (GSH) and oxidized ...
2009 NOV 2 ... 2.7-fold. Activation of NRF2, by KEAP1 knockdown, caused a 75% increase in the amount of glutathione in HaCaT cells and a 1.4- to 1.6-fold increase in their resistance to the electrophiles ... in 23 messenger RNAs (mRNAs) being up-regulated >= 2.0-fold. mRNA for aldo-keto reductase (AKR) 1B10, AKR1C1, AKR1C2 and AKR1C3 were induced to the greatest extent, showing ...
2009 NOV 2 ... Measurements of both reduced and total glutathione levels and the activity of glutathione reductase and glucose-6-phosphate dehydrogenase were performed spectrophotometrically. The results ...
2009 OCT 12 ... effect on the activation of glutathione S-transferase (GST), peroxclase (POD), and glutathione reductase (GR) after treatment with chlorpyrifos, although the effect on GR was attenuated at ...
2009 NOV 26 ... with most phase 2 enzyme inducers, other phase 2 detoxifying enzymes, including GST, glutathione reductase, g-glutamylcysteine synthetase, and heme oxygenase-1, were also induced by ...
2009 NOV 24 ... when exposed to electrophilic quinones, which are capable of depleting cellular reduced glutathione (GSH). Externally added GSH can partially restore the impaired growth of the Delta azoR ... The researchers concluded: "These data indicated that AzoR is a quinone reductase providing resistance to thiol-specific stress caused by electrophilic quinones." ...
2009 NOV 9 ... pregnant women. Moreover, glyoxalase I and II, enzymes that detoxify MG, and glutathione reductase, which generates reduced glutathione, a cofactor for glyoxalase, are also reduced in ...
2009 NOV 9 ... for 24 h resulted in significant increases in the levels of reduced glutathione (GSH), glutathione reductase (GR), and the phase 2 enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1). D3T treatment also ...
2009 NOV 2 ... analysis of flanking genomic sequence, we identify a homologue of gst, which encodes glutathione-S-transferase, immediately downstream of ohr and demonstrate that ohr-gst confers low ... "Previously, we identified the ohr gene encoding organic hydroperoxide reductase as specifically induced during infection of pigs, induced in vitro by organic peroxides ...
