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2009 NOV 27 ... for MART-1-(26-35), a dominant melanoma epitope restricted by human leukocyte antigen (HLA)A* 0201, are exceptionally common in the naive T-cell repertoire. Remarkably, the ...
2009 NOV 23 ... peptide or antinuclear antibodies. Similarly, the presence or absence of the HLA-DRB1 shared epitope or the RA-associated PTPN22 allele had no influence on this ...
2009 NOV 24 ... the phenotype of the HCMV-specific CD8(+) T cells was analyzed by using the CMV pp65 HLA-A*0201 pentamer. A correlation between the proportion of CD28(-) HCMV-specific CD8(+) T ...
2009 NOV 24 ... for AoAS. There were no differences in gender ratio (male: JoAS 81%, AoAS 79%) or in HLA-B27 status (positive: JoAS 75%, AoAS 81%). The axial/peripheral pattern of disease at ...
2009 NOV 23 ... tests have been obtained from each patient. A modified Rodnan skin thickness score, HLA class II genotyping, and a Medsger Damage Index also have been collected. We performed ...
2009 NOV 23 ... by interferon-gamma enzyme-linked immunosorbent spot assay. Intermediate resolution HLA typing was done by polymerase chain reaction. Peptides were also tested by binding assay ...
2009 NOV 23 ... "Our objective was to determine whether the presence of the human leukocyte antigen HLA-DRB1 locus is associated with production of anti-cyclic citrullinated peptide antibodies ...
2009 NOV 24 ... DC with rLZ-8 resulted in the enhanced cell-surface expression of CD80, CD86, CD83, and HLA-DR, as well as the enhanced production of IL-12 p40, IL-10, and IL-23, and the capacity ...
2009 NOV 23 ... dendritic cell (DC) vaccination. In a recently published phase I/II trials, fourteen HLA-A2 negative patients with progressive mRCC were vaccinated with autologous DC pulsed ...
2009 NOV 23 ... of the costimulatory molecules CD80, CD86, and CD40, the maturation marker CD83, and HLA-DR. HNP-1 and HBD-1 also enhanced the production of the proinflammatory cytokines ...
2009 NOV 16 ... According to a study from Reykjavik, Iceland, "The HLA-B8, DR3 haplotype has been associated with high immune reactivity. In this study, we ...
2009 NOV 23 ... ligands (APLs) derived from Ran wild-type epitopes with preferred primary and auxiliary HLA-A*0201 molecule anchor residue replacement. Of the eight tested peptides, the 1Y analog ...
2009 NOV 23 ... memory multifunctional (IFN-gamma+TNF-alpha+IL-2(-)) CD4 T cells, whereas activated HLA-DR+ CD4(+) T cells also increased during IRS. In contrast, dendritic cells decreased ...
2009 NOV 16 ... reported that donor-reactive T-cell responses may decrease during the first year after HLA-mismatched organ transplantation. We wondered whether donor-reactive T-cell responses ...
2009 NOV 23 ... spine (LS) and explore the relationship between sites and extent of inflammation and HLA-B27 status over 12 months." "54 patients with IBP; median duration 24 ...
2009 NOV 16 ... an antigluten T cell response is strongly associated with the histocompatibility antigen HLA-DQ2.5 but is barely associated with HLA-DQ2.2. Yet ...
2009 NOV 16 ... magnitude and half of them targeted different regions of the viral proteome. Strong HLA-B27-restricted CTLs, which have been associated with disease control, were detected in ...
2009 NOV 16 ... high affinity gag-specific TCRs in patients who are positive for the tissue type HLA A02. The specific target of the TCR is the HIV-1 gag epitope SL9 (SLYNVATL) detectable ...
