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2009 NOV 24 ... "In this study, we explore the use of stents as radiating structures to support ... and compared with measurements taken while implanted in a live porcine subject. The in vivo studies of our 2.4-GHz stent-based transmitter, implanted at a depth of 3.5 cm within ... chest. These results are used to explore the accuracy of a high-fidelity simulation model developed using Ansoft's High Frequency Structural Simulator and components of their ...
2009 NOV 24 ... A new study, 'The role of integrin alpha8beta1 in fetal lung morphogenesis and injury,' is now available. "Prenatal inflammation ... medial and caudal lobes as well as abnormalities in airway division. We further show in vivo and in vitro that alpha8-null fetal lung mesenchymal cells fail to form stable adhesions ... complication of preterm birth. We previously demonstrated in a bacterial endotoxin mouse model of BPD that disrupting fibronectin localization in the fetal lung mesenchyme causes ...
2009 NOV 24 ... complexity of endoscopic submucosal dissection (ESD) has limited its implementation in our medical system. to design and evaluate a training program for learning the ESD ... literature, didactic material, and theoretical aspects of ESD; 2) ESD training in an ex-vivo animal model; 3) ESD training in an in-vivo animal model (supervised by ESD expert); and ...
2009 NOV 27 ... According to recent research published in the Journal of Radioanalytical and Nuclear Chemistry, "The radiopharmaceutical ... without evaluation of patient individual characteristics. For a better dose estimate in vivo stability should be considered, because labelled and unlabelled samarium do not have the ... and urine excretion, we calculated the main parameters for a preliminary biokinetic model."Ridone and colleagues published their study in the Journal of ...
2009 NOV 24 ... In this recent study, researchers in Tubingen, Germany conducted a study "To investigate ... of methyl blue and aniline blue as vital dyes for vitreoretinal surgery in an in vivo rat model and to evaluate the effect of these dyes on retinal structure and function. ...
2009 NOV 24 ... from the United States, "NKT cells have been shown to promote peripheral tolerance in a number of model systems, yet the processes by which they exert their regulatory ... To confirm their noninflammatory effects, NKT-instructed APCs were tested in an in vivo assay that depends on the activation of antigen-specific human T cells. Control DCs ...
2009 NOV 24 ... "Lipid and protein sorting and trafficking in intracellular pathways maintain cellular function and contribute to organelle ... results are likely to be relevant to the molecular sorting of membrane components in vivo."Tian and colleagues published their study in Biophysical Journal (Bending ... with a flat reservoir to be a quadratic function of curvature. In this analytical model, the degree of sorting is determined by the ratio of two thermodynamic derivatives. ...
2009 NOV 25 ... "Electrochemotherapy and electrogene therapy are new methods in molecular medicine based on electroporation-mediated introduction of foreign molecules ... introduction of foreign molecules (chemotherapeutic drugs, DNA) into target cells in vivo. Electrochemotherapy involves the injection of chemotherapeutic agent followed by a ... for electroporation-based treatments. The analysis is based on a coupled electrothermal model using 3-D finite-element approach. We studied two electrode geometries: parallel plates ...
2009 NOV 25 ... According to recent research published in the journal Molecular Pharmaceutics, "Herein we report on the potencies of 4 related ... Reddy and colleagues published their study in Molecular Pharmaceutics (In Vivo Structural Activity and Optimization Studies of Folate-Tubulysin Conjugates. Molecular ... the natural tubulysin B drug proved to be inactive against a human nasopharyngeal tumor model when administered at doses near to or greater than the maximum tolerated dose (MTD). ...
2009 NOV 27 ... and magnitudes of turnover processes.""Here we present a new method in which stable isotope additions (D2O or (NaHCO3)-C-13) are used to follow the invivo ... DMSP was monitored using a proton-reaction-transfer mass spectrometer (PTR-MS). A growth model was developed to calculate specific DMSP synthesis rates from the progress in mass ratio ...
2009 NOV 24 ... "The opportunistic pathogen Pseudomonas aeruginosa causes a variety of infections in immunocompromised individuals, including individuals with the heritable disease cystic ... genes potentially involved in alanine catabolism (dadA and dadX) are induced during in vivo growth in the rat peritoneum and during in vitro growth in sputum (mucus) collected from ... mutant unable to catabolize DL-alanine displays decreased competitiveness in a rat lung model of infection." Boulette and colleagues published their study in the ...
2009 NOV 25 ... According to recent research published in the journal IEEE Transactions on Nuclear Science, "Rapid multi-tracer PET, where two to ... and complementary information has the potential to improve tumor characterization in vivo, warranting further investigation of rapid multi-tracer techniques."Black ... plus one or two of these shorter-lived secondary tracers was evaluated in the same tumor model. Dynamic PET imaging was performed in four dogs with pre-existing tumors, and the raw ...
2009 NOV 25 ... According to recent research published in the journal Learning & Memory, "The storage of stable memories is generally considered ... glomerular volume under confocal microscopy, and odor-evoked activity, using in vivo calcium imaging. We show that long-term olfactory memory for a given odor is associated ... we show that structural glomerular plasticity can be predicted based on a putative model of interglomerular connections."Hourcade and colleagues published their ...
2009 NOV 24 ... motors, which transport organelles and other cargoes along cytoskeleton tracks. In this work, we use single particle tracking to study the invivo regulation of the ... previous models that only consider active transport. We proposed a transport-diffusion model in which melanosomes may detach from actin tracks and reattach to nearby filaments to ...
2009 NOV 25 ... is an obligatory component of NMDARs without a known functional homolog and is expressed in almost every neuronal cell type. The NMDAR system is a coincidence detector with ... gyrus (DG) of the hippocampal formation. Early LTP was expressed normally in area CA1 in vivo, but was completely suppressed at perforant path-granule cell synapses in the DG. In ... induction of hippocampal long-term potentiation (LTP). We have generated a mutant mouse model expressing a hypomorph of the Grin1(N598R) allele, which leads to a minority (about 10%) ...
2009 NOV 24 ... "The superiority of endoscopic surgery over traditional open surgery in many areas has encouraged researchers to tackle a few shortcomings that are associated ... study in IEEE Sensors Journal (MEMS Endoscopic Tactile Sensor: Toward In-Situ and In-Vivo and Tissue Softness Characterization. IEEE Sensors Journal, ... was characterized before the microfabrication of the corrugated sensor. A finite-element model of the sensor system and soft material was also developed," wrote S. Sokhanvar and ...
2009 NOV 24 ... to disease, but the developmental basis of dimorphisms is poorly understood. In these studies, we focused on the anteroventral periventricular nucleus (AVPV), a nucleus ... for sexual differentiation of the AVPV, we used targeted apoptosis microarrays and in vivo and in vitro follow-up studies. We found that the tumor necrosis factor alpha (TNF ... The researchers concluded: "These findings form the basis of a new model of sexual differentiation of the AVPV that may also apply to the development of other ...
2009 NOV 26 ... In this recent study, researchers in Hongo, Japan conducted a study "To investigate the ... stromal discs." "Three insertion techniques were assessed in an ex vivomodel. The feasibility of DSAEK grafts with cultured HCECs was examined in a rabbit ...
2009 NOV 23 ... intestinal permeation maybe affected by interactions on membrane transporters expressed in the intestinal epithelial cells." "The purpose of the present study was ... impact of interactions related to transporters in the Caco-2 cell model versus the in vivo rat model of intestinal absorption. In both models, it was investigated whether ...
2009 NOV 23 ... more about why certain neurologic disorders, such as migraine headaches and psychosis in schizophrenic patients, occur and provide insight into how to best treat them, according ... associated with migraines. In the article, "11C-PK11195 PET for the In Vivo Evaluation of Neuroinflammation in the Rat Brain After Cortical Spreading Depression," ... in Japan were the first to noninvasively visualize neuroinflammation in an animal model of migraine using a PET technique. Neuroinflammation is thought to be a key factor in ...
