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2009 NOV 24 ... "In this study, we explore the use of stents as radiating structures to support ... and compared with measurements taken while implanted in a live porcine subject. The in vivo studies of our 2.4-GHz stent-based transmitter, implanted at a depth of 3.5 cm within ... implant location is chosen for the specific application of heart failure detection by monitoring internal pressure measurements of the pulmonary artery," researchers in the United ...
2009 NOV 9 ... (USPIO dose and echo time) were determined by USPIO dose-dependent studies ex vivo and invivo. Improved analysis strategies were at first applied for cerebral BV estimation in ... treatment outcome has led to efforts to develop non-invasive methods for longitudinal monitoring of tumor microvasculature. We describe a steady-state MRI technique to determine ...
2009 NOV 9 ... According to recent research published in the journal Medical Physics, "Endocavitary high intensity contact ultrasound (HICU) may ... tuning errors in the controller's parameters and against input noise, through ex vivo experimental studies and through numerical simulations in which nonlinear response of ... permits both excellent targeting of the pathological volume and accurate preoperatory monitoring of the temperature elevation." "In this article, the authors address the ...
2009 NOV 16 ... vesicular stomatitis virus (VSV) oncolytic vector would transduce more tumor cells invivo, that coexpression of the immunostimulatory IFN-beta gene would enhance the ... therapy compared with VSV alone, dependent in part on host CD8+ T-cell responses. Immune monitoring suggested that these antitumor T-cell responses may be due to a generalized T-cell ...
2009 NOV 24 ... "Nuclear factor kappa B (NF-kappa B) is a transcription factor that plays a major role in many human disorders, including immune diseases and cancer. We designed a reporter ... provides a powerful tool for monitoring NF-kappa B activity in real time in vitro and in vivo." Badr and colleagues published their study in Molecular Imaging ...
2009 NOV 16 ... "In a companion study, the authors describe the development of a new instrument named the ... adenosine. Proof-of-principle analyses included noise assessments and in vitro and in vivo measurements that were compared with similar analyses by using a commercial hardwired ... detection of dopamine, adenosine, and glutamate for intraoperative neurochemical monitoring Laboratory investigation. Journal of Neurosurgery, 2009;111(4):701-711). ...
2009 NOV 23 ... stability were verified by molecular analyses. Replication and oncolysis were evaluated in ovarian cancer cells. Fusion functionality was confirmed by in vitro gamma camera and ... enzymatic activity of HSV-tk as the virus effectively phosphorylated thymidine both ex vivo and in vitro. In vitro fluorescence imaging demonstrated a strong correlation between ... Oncolytic Adenovirus with a Capsid-Incorporated Dual-Imaging Moiety for Monitoring Virotherapy in Ovarian Cancer. Molecular Imaging, 2009;8(5):264-277). For ...
2009 NOV 16 ... food industry. However, the application of functional excipients that are established in pharmaceutical applications is limited in case of food products, as they are typically ... were determined by using Magnetic Marker Monitoring. The results of in vitro and in vivo investigations show that both types of microcapsulles are resistant to gastric juice for ...
2009 NOV 16 ... According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of ... caspases, notably caspase-3, is probably the most attractive for developing specific in vivo molecular imaging probes. We recently designed a library of isatin-5 sulfonamides and ... of tumor apoptosis that could find utility in anticancer drug development and the monitoring of early responses to therapy." Nguyen and colleagues published their ...
2009 NOV 16 ... (CFM) for real-time, spatially and chemically resolved neurotransmitter measurements in the brain. The FSCV study consisted of a triangle wave scanned between -0.4 and 1 V at a ... Proof-of-principle tests included in vitro flow injection and noise analysis, and in vivo measurements in urethane-anesthetized rats by monitoring dopamine release in the ...
2009 NOV 23 ... on gastric neurocircuits have not, however, been fully investigated," investigators in the United States report. "A high density of GLP-1 containing neurones and ... - London (Vagally mediated effects of glucagon-like peptide 1: in vitro and in vivo gastric actions. Journal of Physiology - London, 2009;587(19):4749-4759). ... and microinjection in the dorsal vagal complex (DVC) of anaesthetized rats while monitoring gastric tone. Perfusion with GLP-1 induced a concentration-dependent excitation of a ...
2009 NOV 9 ... immunized monkeys with simian immunodeficiency virus (SIV) or monitoring infection rates in large human trials. Although conventional parameters of vaccine-induced immune responses ... with DNA replication-defective adenovirus vector expressing various SIV genes, as an ex vivo model, to mimic the effects of different immune effector functions on viral infection. ...
2009 NOV 16 ... conjugates targeted to tumor endothelium using synthetic oligopeptides,' are discussed in a new report. "Synthesis and characterization of N-(2-hydroxypropyl)methacrylamide ... have been studied in vitro using various cell lines (EA.hy926, 3T3, SW620, and EL4). In vivo accumulation of the conjugate specifically targeted with cyclo(RGDfK) within the tumor ... report. "The polymers were labeled with a fluorescent dye to enable monitoring of the interaction of the polymer conjugate with cells using fluorescence microscopy. ...
2009 NOV 9 ... Cornelissen and colleagues published their study in Nuclear Medicine and Biology (In vivo monitoring of intranuclear p27(Kip1) protein expression in breast cancer cells during trastuzumab ...
2009 NOV 10 ... the nucleus, the 3'-end processing complex is removed by a poorly described mechanism. In this study, we asked whether factors involved in mRNP maturation and export are also ... Rna14p. RNAs that become processed in a mex67 mutant have longer poly(A) tails both in vivo and in vitro. This influence of Mex67p on 3'-end processing is conserved, as depletion ... investigators in Aarhus, Denmark report. "An RNA immunoprecipitation assay monitoring the amount of the cleavage factor (CF) IA component Rna15p associated with poly(A)(+) ...
2009 NOV 2 ... Fresh data on localized scleroderma are presented in the report 'Multiphoton laser scanning microscopy of localized scleroderma.' "A ... scanning microscopy (MPLSM) for diagnosing LS and monitoring the treatment response in vivo," scientists in Fuzhou, People's Republic of China report. "Three ...
2009 NOV 2 ... "Liver dysfunction affects a variety of metabolic pathways in the critically ill, but mechanisms remain poorly understood. We prospectively assessed ... assessed markers of hepatic injury and function in sepsis and I/R injury in vivo and molecular mechanisms in human liver tissue ex vivo," scientists in Jena, Germany ... of transporter proteins for bilirubin and ICG in cultured human liver tissue, and (b) monitoring uptake and excretion of the dye after I/R injury in 12 patients receiving a biliary ...
2009 NOV 9 ... receptor (VEGFR) expression may also mediate AAA growth and rupture," investigators in the United States report. "We examined VEGFR expression as a function of ... study in Arteriosclerosis Thrombosis and Vascular Biology (Analysis of In Situ and Ex Vivo Vascular Endothelial Growth Factor Receptor Expression During Experimental Aortic ... "Clinical VEGFR expression imaging strategies, if feasible, may improve real-time monitoring of AAA disease progression and response to suppressive strategies. (Arterioscler Thromb ...
2009 NOV 23 ... VisEn Medical Inc., a leader in fluorescence invivo imaging from research through medicine, announced the commercial ... the commercial launch of its new Cat B 750 FAST™ imaging agent for measuring and monitoring cathepsin B activity associated with disease progression and therapeutic response in ...
