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2009 NOV 29 ... function is now identified in mice, involving the impairment of cyclic-AMP- and protein-kinase-A-dependent forms of synaptic plasticity, or readiness for cognitive ...
2009 NOV 26 ... of glucose in C2C12 myotubes, which was associated with both AMP-activated protein kinase (AMPK) and phosphatidylinositol 3-kinase (PI3-K) ...
2009 NOV 27 ... where the substrate is an enzyme, such as in phosphorelay and mitogen-activated protein kinase pathways. We illustrate this for the important example of the phosphotransferase system ...
2009 NOV 24 ... phenotype. In addition, we report that two survival-promoting kinases, protein kinase C zeta and phosphoinositide-dependent protein kinase 1, ...
2009 NOV 29 ... tangles (NFT), in the brain. Previous research has suggested that glycogen synthase kinase-3 (GSK-3), an enzyme that is essential for many critical cellular functions, may play a ...
2009 NOV 24 ... we demonstrate that silibinin can block the activation of NF-kappa B, c-Jun N-terminal kinase (JNK), p38 mitogen-activated protein (MAP) kinase, and ...
2009 NOV 24 ... focal adhesion sites using fluorescently tagged anti-pFAK (phosphorylated focal adhesion kinase). The 16 mu m grain size etched specimens had significantly (P < 0.01) higher number of ...
2009 NOV 24 ... Interleukin-8 production was slightly decreased, and activation of c-Jun N-terminal kinase, a mitogen-activated protein kinase, was reduced in ...
2009 NOV 24 ... report. "Here we report the involvement of the S. mutans VicK sensor kinase in both the acidogenicity and the aciduricity of this bacterium. When cultures were ...
2009 NOV 27 ... are major downstream targets. The activity of mTOR effector 70-kDa ribosomal protein S6 kinase (p70S6K) specifically increases in the axon during neuronal polarity formation. The mTOR ...
2009 NOV 24 ... in Matrigel implants. Furthermore, two small molecule inhibitors of the PDGFR tyrosine kinase (i.e., imatinib and dasatinib) exerted negative effects on fSMC and mSMC growth in ex ...
2009 NOV 24 ... (BR) regulates gene expression and plant development through a receptor kinase-mediated signal transduction pathway(1). Despite the identification of many components ...
2009 NOV 27 ... expression. Hepatic DAX-1 expression is increased by insulin and SIK1 (salt-inducible kinase 1), whereas it is decreased in high fat diet-fed and diabetic mice. ...
2009 NOV 24 ... phospholipase C, phosphatidylinositol 4,5-biphosphate, diacylglycerol, and protein kinase C in primary hPASMCs. The ET-1 effect on membrane potential and TASK-1 was abrogated ...
2009 NOV 26 ... factor 2 (Nrf2) was stimulated by the compound and attenuated by phosphatidylinositol 3-kinase inhibitors such as LY294002 and wortmannin," wrote J.Y. Seo and colleagues, Kyungpook ...
2009 NOV 27 ... binding) and phosphorylate Rap1b on Ser(179) at its C terminus. cAMP-dependent protein kinase (PKA)-mediated phosphorylation of Rap1b is required for cAMP-dependent mitogenesis, ...
2009 NOV 25 ... "Using a bacterial infection model in Drosophila, we uncovered a p38 MAP kinase-mediated mechanism of tolerance to intracellular bacterial infection as measured by the ...
2009 NOV 27 ... of Semaphorin3A (Sema3A), a repulsive axon guidance molecule. Fyn, a Src-type tyrosine kinase, is involved in the Sema3A signaling.""However, the relationship between ...
2009 NOV 27 ... of the C-terminal fragments of TDP-43, whereas inhibition of mTOR, a key protein kinase involved in autophagy regulation, reduces the 25-kDa C-terminal fragment accumulation ...
2009 NOV 24 ... from Calcutta, India, "In legume-rhizobia symbiosis, Ca2+/calmodulin-dependent protein kinase (CCaMK) is essential for rhizobial invasion through infection threads in the epidermis ...
