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2009 NOV 2 ... to recent research published in the journal Analytical Chemistry, "Cyclooxygenase, lipoxygenase, and epoxygenase derived oxylipins, especially eicosanoids, play important roles in many ...
2009 NOV 2 ... development of type 2 diabetes, atherosclerosis, and the metabolic syndrome. The 12/15-lipoxygenase (12/15-LO) enzyme has been linked to inflammatory changes in blood vessels that precede ...
2009 NOV 16 ... of melanoma cells, having no effect on melanoma proliferation in vitro. Inhibition of 5-lipoxygenase (5-LOX) seems to have a pivotal role in this model because caffeic acid and MK886, a ...
2009 NOV 23 ... the lipid oxidation product 4-hydroxynonenal (4-HNE) as well as increased expression of lipoxygenase and peroxisome proliferator-activated receptor-gamma (PPAR gamma) in the murine ...
2009 NOV 23 ... pain. We found that the number of motifs which describe the colocalization of 5-lipoxygenase (5-LO) or 12-LO with other proteins increased disproportionally after dipyrone ...
2009 NOV 2 ... line is caused by a mutation in Loxhd1. LOXHD1 consists entirely of PLAT (polycystin/lipoxygenase/alpha-toxin) domains and is expressed along the membrane of mature hair cell ...
2009 NOV 1 ... in murine and human platelets. Also, 12-HpETE, a peroxide synthesized in the platelet lipoxygenase pathway, induced TACE-mediated receptor cleavage. The TACE activation was independent of ...
2009 NOV 1 ... and women, between seven single nucleotide polymorphisms (SNPs) in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and 12 SNPs in the leukotriene A4 hydrolase (LTA4H) ...
2009 NOV 16 ... first time from this plant. These compounds were screened for their antiinflammatory and lipoxygenase inhibitory activities," wrote M.I. Choudhary and colleagues, University of Karachi. ...
2009 NOV 2 ... acids, their antimicrobial activities, and their ability to inhibit urease and soybean lipoxygenase activities. Ibuprofen and fenoprofen hydroxamic acids with free hydroxy groups present ...
2009 NOV 23 ... research published in the Journal of Medicinal Chemistry, "The potent and selective 5-lipoxygenase-activating protein leukotriene synthesis inhibitor ...
2009 NOV 2 ... of resveratrol and propenoic acid derivatives. In vitro cyclooxygenase (COX)/5-lipoxygenase (5-LOX) inhibition assays showed that the test compound exhibited a dual inhibitory ...
2009 NOV 3 ... The predominant VOCs emitted after inoculation were volatile products from the lipoxygenase pathway (LOX products). The increased emission of LOX products proved to be a strong ...
2009 NOV 2 ... evaluate the antioxidant activity. Inhibition of both prostaglandin E-2 production and lipoxygenase were used to assess the anti-inflammatory activity. Antimicrobial activity was studied ...
2009 NOV 2 ... "Allosteric regulation of human lipoxygenase (hLO) activity has recently been implicated in the cellular biology of prostate cancer. ...
2009 NOV 2 ... New investigation results, 'Kukoamine A analogs with lipoxygenase inhibitory activity,' are detailed in a study published in Journal of Enzyme Inhibition ...
2009 NOV 9 ... According to recent research from South Korea, "Cyclooxygenase (COX) and lipoxygenase (LOX) can catalyze the oxidation of C20 fatty acids to produce certain eicosanoids, ...