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2009 NOV 23 ... intrauterine growth, as reflected by a marked reduction in fetal lung, heart, and liver weights, and by low body weight at birth. Importantly, we found that insulin-like growth ... 3 (Erk3) is an atypical member of the mitogen-activated protein (MAP) kinase family. No function has yet been ascribed to this MAP kinase," scientists in Montreal, Canada report. ...
2009 NOV 23 ... research will be conducted in the future by creating vastly improved models of liver function in order to study and treat liver diseases, such as hepatitis and cirrhosis, and improve ...
2009 NOV 23 ... of GNRs in the explanted organs, and found most GNRs resided in the macrophages in liver and spleen."Tong and colleagues published their study in Langmuir ... high speed and submicrometer resolution allowed for studying the clearance of GNRs as a function of surface coating. PEGylated-GNRs (PEG-NRs) were found to exhibit a biphasic clearance ...
2009 NOV 24 ... embryos supplied with functionally normal placentas can be born alive. Fetal liver hypoplasia thought to be responsible for the embryonic lethality of IRE1 alpha-null mice ... The researchers concluded: "These findings reveal that IRE1 alpha plays an essential function in extraembryonic tissues and highlight the relationship of physiological ER stress and ...
2009 NOV 23 ... Xenopus laevis (55.27%) and Danio rerio (47.69%). The hl gene was expressed only in liver tissue and not in heart, spleen, kidney and brain tissues. Further analysis of yak HL ... to a study from Chengdu, People's Republic of China, "In order to study the biological function of hepatic lipase (hl) gene in yak, the cDNA sequence encoding hepatic lipase from yak ...
2009 NOV 23 ... thoracic duct in certain diseases suspected to involve an abnormal load of chyle (liver, heart, and inflammatory bowel diseases). The study was approved by the institutional ... by anatomic structures was established. Dynamic imaging of the chyle flow and valve function was possible. The thoracic duct was visualized in 564 (96%) of 585 examinations. The ...
2009 NOV 27 ... throughout the body harbor circadian clocks."These peripheral clocks, such as in the liver and heart, regulate local rhythms of biochemistry and physiology, but are kept in a ... its daily cycling from high to low levels. ID2 is a transcription facto, so its primary function is to regulate when genes are switched on or off. And, as this process changes on a ...
2009 NOV 23 ... months of weight loss, OSA was assessed together with CT-quantified intra-abdominal and liver fat and markers of metabolic and cardiovascular function. At 6 months, weight loss and ...
2009 NOV 23 ... sapiens (77.83%) and Mus musculus (72.19%), respectively. tf gene was expressed only in liver tissues. It also contained two conserved TF domains: one is in its N-terminal (25 ... concluded: "The results of this study suggested that tf gene of yak plays the same function as other species."Chen and colleagues published their study in the Journal ...
2009 NOV 23 ... against insulinoma-associated protein 2 (IA2) and/or GAD. In one of them, a liver biopsy during posttransplant year 2 showed B-cell accumulations near insulin-positive ... characteristics at the time of transplantation are correlated with inadequate graft function." "Thirty nonuremic C-peptide-negative type 1 diabetic patients had ...
2009 NOV 23 ... to these mechanisms in two clinically important target organs, namely uterus and liver," scientists writing in the journal Molecular Endocrinology report. "We ... alpha DBD. The phenotype of the ER alpha((EAAE/EAAE)) mice resembles the general loss-of-function phenotype of alpha ER knockout mutant mice with hypoplastic uteri, hemorrhagic ovaries, ...
2009 NOV 23 ... 6 (STAT6). Our study was aimed at evaluating the lack of STAT6 signaling on liver homeostasis. To this end we analyzed the liver proteome of wild type and STAT6 knock-out ... Research (Differential Proteomic Analysis of STAT6 Knockout Mice Reveals New Regulatory Function in Liver Lipid Homeostasis. Journal of Proteome Research, 2009;8(10):4511-4524). ...
2009 NOV 23 ... during ALF, we subjected seven female pigs to surgical liver devascularization. Liver function biochemical markers, thyroid hormones, endogenous opioids, malondialdehyde (MDA), and ...
2009 NOV 23 ... journal Clinical Microbiology and Infection report. "Similar to nonviral liver diseases, HBV and HCV infection can cause chronic injury to the liver, with subsequent ... Furthermore, HBV can be integrated into the host genome, leading to changes in genomic function or chromosomal instability. By contrast to HBV, HCV cannot integrate into the host ...
2009 NOV 23 ... to study effects of typical antipsychotics and atypical antipsychotics in the postmortem liver of schizophrenia patients using microarrays (Affymetrix U133 plus2.0)," researchers in ... further identified genes associated with lipid metabolism and mitochondrial function. Analyses on individual antipsychotics revealed a set of genes (151 transcripts, FDR ...
2009 NOV 23 ... screening efficiency at medical checkups. This study examined the seasonal variation in liver function tests using recently described data-mining methods." "The 'latent ...
2009 NOV 23 ... The results showed that DPT mRNA was strongly expressed in human fetal and adult liver, kidney, and spleen, weakly in ovary and heart, and absent in other tissues and HCC cell ... (HCC) based on the analysis for DPT gene in normal tissues in order to estimate its function in the progression of HCC. DPT mRNA expression was analyzed in normal tissues and HCC ...
2009 NOV 23 ... published in the journal Annals of Clinical Biochemistry, "In patients with chronic liver disease (CLD), glycated haemoglobin (HbA(1C)) levels have been shown to be apparently ... study was aimed to examine whether both glycaemic indices are influenced by hepatic function." "Subjects consisted of 82 patients with CLD. Various indicators for ...
2009 NOV 23 ... drugs because they are eventually cleared through the kidneys after metabolism in the liver," wrote R.H. Howland and colleagues, University of Pittsburgh, Western Psychiatric ... distribution shifts toward greater drug accumulation in fat stores. Decrease in renal function with age is especially important regarding, the use of lithium but is also relevant for ...
