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2009 NOV 16 ... FG-3019, and appeared to reach a plateau after 8-10 weeks of dosing. Sodium restriction, losartan, and hydrochlorothiazide reduce elevated urinary CTGF/CCN-2 levels in patients with ...
2009 NOV 23 ... for 6 h with increased doses of the following drugs: hydrochlorothiazide, atenolol, losartan, telmisartan, captopril, and nifedipine. Adiponectin levels, as well as adiponectin-mRNA ...
2009 NOV 16 ... and Smad-dependent gene transcription. The angiotensin type 1 (AT1) antagonist losartan diminished Ang II-induced Smad activation. The blockade of endogenous transforming ...
2009 NOV 9 ... 50% of the GFP-containing neurons, an effect that was abolished by the AT1R antagonist losartan (1 mu mol/L). Consistently, 9 of 28 GFP/PAG-expressing neurons contained AT1R mRNA, as ...
2009 NOV 2 ... enalapril, as well as preventive or therapeutic application of the AT1R antagonist losartan, resulted in a significantly ameliorated course of MOG-EAE. Blockade of AT1R did not ...
2009 NOV 10 ... a day for 13 days. Probe drugs used to measure CYP activities were caffeine (CYP1A2), losartan (CYP2C9), omeprazole (CYP2C19), dextromethorphan (CYP2D6), chlorzoxazone (CYP2E1) and ...
2009 NOV 9 ... [13] years) were randomized into 2 groups of 25 patients each; 1 group was treated with losartan for 1 year, and the other was not (control group)," scientists writing in the journal ...
2009 OCT 20 ... preparations and human serum containing drugs, tranexamic acid together with losartan potassium are proposed, using acetonitrile: water (50:50), adjusting pH to 2.6 with ...
2009 OCT 20 ... *33 (R132Q), and *34 (R335Q), were assessed using three substrates ( diclofenac, losartan, and glimepiride)." "When expressed in a baculovirus-insect cell system, ...
2009 NOV 9 ... gene, which was blocked by the addition of an Ang II type 1 receptor antagonist (losartan) and inhibitors to extracellular signal-regulated kinase 1/2 (PD98059) and p38 ...
2009 NOV 23 ... we employed a selective small interfering RNA (siRNA, 50 nM) or an AT(1)R blocker (Losartan, 1 mc M) to evaluate the specific role of this receptor in primary cultures of neonatal ...
2009 NOV 2 ... reduction, a time of established injury, rats were given vehicle, RWJ-676070, enalapril, losartan, RWJ-676070 plus enalapril, or losartan in drinking ...
2009 NOV 1 ... (1 mg.kg(-1).day(-1)) or injected subcutaneously daily (100 mg.kg(-1).day(-1)) with losartan. LV dimensions and function were assessed at 4 wk and at 6 wk post- MI, i.e., 2 wk after ...
2009 NOV 2 ... atherosclerosis and intimal thickening. In the present study, we examined the effects of losartan, an angiotensin AT(1) receptor antagonist, on the development of IEL defects," ...
2009 NOV 9 ... "We investigated the effects of the angiotensin II type 1 receptor antagonist losartan and its metabolites (EXP3174 and EXP3179) on NADPH oxidase activity and MMP-9 secretion ...
2009 OCT 19 ... receptor mRNA, but not that of the AT2 receptor. The angiotensin AT1 receptor antagonist losartan blocked the effects of ADT-induced cell proliferation, TGF-beta 1 and collagen type IV ...
2009 NOV 16 ... Some, but not all, of the binding could be displaced by the AT(1)-selective antagonist losartan," wrote V.T. Karamyan and colleagues, University of Mississippi. The ...
