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2009 NOV 23 ... 1-phosphate (S1P) is a sphingolipid metabolite which is readily generated in mast cells and has been demonstrated to be an important regulator of allergen-induced mast cell ...
2009 NOV 23 ... in the serum and infiltration of eosinophils into the conjunctiva. The role of IgE and mast cells in allergic conjunctivitis is largely unknown, however." "We investigated ...
2009 NOV 23 ... "Wang ZY, Wang P, Bjorling DE. Role of mast cells and proteaseactivated receptor-2 in cyclooxygenase-2 expression in urothelial cells," ...
2009 NOV 30 ... cells. In this study, we show that the CD43 ectodomain is shed from murine granulocytes, mast cells, and T cells, but not from macrophages." "To study the significance of ...
2009 NOV 30 ... to methacholine than C57BL/6 mice. Moreover, BALB/c mice exhibited higher numbers of mast cells in lung tissue when compared to C57BL/6. On the contrary, eosinophil and neutrophil ...
2009 NOV 30 ... scratching, an itch-associated response, which was not suppressed by a deficiency in mast cells or the H(1) histamine receptor antagonist terfenadine. The action of SPC was inhibited ...
2009 NOV 30 ... that Langerhans cells are mandatory for CD8+ T-cell priming. They have also introduced mast cells as a pivotal actor in the magnitude of the inflammatory reaction," wrote M. Vocanson ...
2009 NOV 30 ... muscle in the asthmatic airway remains to be established. beta(2)-Agonists can inhibit mast cell mediator release, but this response is susceptible to desensitization, a process ... the nucleus, resulting in increased CS-mediated gene transcription. In structural airway cells, such as fibroblasts and smooth muscle, this gene transcription is associated with the ...
2009 NOV 24 ... presumably causing hyperpolarization can affect histamine release from rat peritoneal mast cells. The effect of KCOs on compound 48/80-induced response appears to be potentiation in ...
2009 NOV 23 ... resulted in significantly greater serum IgE, BLG-specific IgG1, RMCPII and intestinal mast cells but reduced MLN Foxp3(+) cells, Foxp3, and CCR7 expression and ileal cytokines, ...
2009 NOV 23 ... and thrombocytopenia," scientists in Akita, Japan report. "Atypical mast cells (CD2+, CD25+, CD117+) with toluidine blue metachromasia were found in the peripheral ...
2009 DEC 1 ... "Since a wide variety of heterogeneity was found in tissue mast cells, recent studies have focused on the process of differentiation and maturation of...
2009 NOV 30 ... IgE resulting from omalizumab treatment leads to reductions in FcepsilonRI expression on mast cells, basophils and dendritic cells. This combined effect results in attenuation of several ...
2009 NOV 16 ... to a study from Oviedo, Spain, "Peripheral interactions between nociceptive fibers and mast cells contribute to inflammatory pain, but little is known about mechanisms mediating ...
2009 DEC 1 ... According to recent research published in the journal Diagnostic Pathology, "Mast cells reside within the connective tissue of a variety of tissues and all vascularized organs. ...
2009 NOV 16 ... the diagnostic value of this antibody. were also stained for tryptase to identify mast cells, which are CD117 positive. In addition, S 100 and CD I a stains were performed to assess ...
2009 NOV 27 ... "In response to various exogenous stimuli, mast cells (MCs) release a wide variety of inflammatory mediators stored in their cytoplasmic ...
2009 NOV 30 ... of macrophages and T lymphocytes. Relatively little is known about the role of mast cells and their mediators in the pathogenesis of sarcoidosis." "Tryptase is an ...
2009 NOV 23 ... through experiments in genetically modified mice and supported by biochemical studies of mast cells derived from these mice. These studies have revealed that signaling pathways exist to ...
