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2009 OCT 20 ... reveals a convex membrane-binding surface, suggesting a hypothesis for negative membrane curvature induction in the nascent intralumenal vesicle." Im and colleagues ...
2009 OCT 12 ... 18, and partly for keratin 7, but were negative for keratins 5/6, 20 and epithelial membrane antigen. The spindle cells were positive for vimentin and CD10. All components were ... in the United States report. "Two tumors were located in the greater curvature in the gastric body and one in the antrum. The tumors measured 5, 6, and 15 cm in ...
2009 OCT 19 ... can be discerned during poxvirus morphogenesis. The crescents consist of a lipoprotein membrane and an outer lattice scaffold, which provides uniform curvature." ...
2009 NOV 3 ... and spindle assembly assays in Xenopus laevis egg extracts, we show that epsin-induced membrane curvature is required for proper spindle morphogenesis, independent of its function in endocytosis ...
2009 NOV 21 ... progression of endocytic events leading to vesicle scission. The central idea is that membrane curvature is coupled to the accompanying biochemical reactions. This coupling ensures that the ...
2009 NOV 24 ... a continuum model couples the forces of cell-substrate adhesion, actin polymerization, membrane curvature, and the flux of calcium through the membrane. Linear stability analysis shows that ...
2009 NOV 17 ... to a study from the United States, "F-BAR domains bind curved membranes and induce membrane invagination." "In a recent Cell paper, Guerrier et al. describe an ... Guerrier et al. describe an ''inverse'' F-BAR family member that induces outward curvature and filopodia in migrating neurons," wrote B. Carlson and colleagues, Duke University, ...
2009 NOV 24 ... of tube radii, and demonstrate that the stiffness of ternary lipid mixtures depends on membrane curvature for a large range of lipid compositions. This observation indicates amplification by ...
2009 NOV 2 ... hydrolysis products that alter curvature and permeability of the pre-synaptic membrane. Here, we report results deriving from the first chemical analysis of the action of ...
2009 SEP 29 ... Structural elements associated with the stator followed the curvature of the cytoplasmic membrane. The rotor and the C ring also exhibited angular flexion, resulting in a slight ...
2009 OCT 13 ... "Peripheral membrane proteins of the Bin/amphiphysin/Rvs (BAR) and Fer-CIP4 homology-BAR (F-BAR) family ... The degree of membrane bending appears to be encoded in the structure and immanent curvature of the particular protein domains, with BAR and F-BAR domains inducing high-and ...
2009 SEP 29 ... in recruiting other endocytic proteins, binding of ubiquitylated cargo and induction of membrane curvature. These molecules bear a characteristic epsin N-terminal homology (ENTH) domain and ...
2009 OCT 20 ... "Decades ago it was proposed that exocytosis involves invagination of the target membrane, resulting in a highly localized site of contact between the bilayers destined to fuse. ... Here, we directly address this question by utilizing vesicles with different degrees of curvature. A tubulation-defective syt mutant was able to promote fusion between highly curved ...
2009 NOV 24 ... "We use a self-consistent mean-field theory, designed to investigate membrane reshaping and lipid demixing upon interaction with proteins, to explore BAR domains ... will occur only for membrane patches that have the inherent propensity for high curvature, reflected in the tendency to create local distortions that closely match the curvature ...
2009 NOV 16 ... generation of wedge-shaped lysolipids, with the resulting local positive membrane curvature. We show that the arrival of cargo at the Golgi complex induces the recruitment of Group ...
2009 OCT 13 ... that dictate localization are largely unknown. Recent evidence has shown that positive membrane curvature can serve as a cue for localization of a peripheral membrane protein," investigators in ...
2009 OCT 6 ... A new study, 'A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole,' is ... they act to bind the PVM preferentially, possibly through sensing its strong negative curvature," wrote M.L. Reese and colleagues, Stanford University, Department of Microbiology & ...
