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2009 MAR 10 ... The cultured teeth phenocopy the extra incisors phenotype of the Sostdc1-deficient mice. Furthermore, we show that minimizing the amount of dental mesenchyme in cultured ... "Like epithelial organs in general, tooth development involves inductive crosstalk between the epithelium and the mesenchyme. ... incisors by minimizing the amount of mesenchymal tissue surrounding the incisor tooth germs prior to culture in vitro. The cultured teeth phenocopy the extra incisors phenotype of ...
2009 MAY 12 ... cells. To pursue this goal, we re-associated the palatal epithelium from young mice with the odontogenic dental mesenchyme and transplanted the re-associated tissues into ... "A bioengineered tooth would provide a powerful alternative to currently available clinical treatments. ... treatments. Previous experiments have succeeded in bioengineering teeth using tooth germs from animal embryos," scientists writing in the Journal of Dental Research report.
...
2007 OCT 2 ... scaffold.
"Heterogeneous cells dissociated from embryonic day 14 (E14) mice tooth germs were seeded on a scaffold and implanted under a kidney capsule in adult mice. The ...
2008 APR 1 ... "To identify the role of Epfn in tooth development, we created Epfn-deficient mice (Epfn-/-). Epfn-/-mice developed an excess number of teeth, enamel deficiency, defects ... defects in cusp and root formation, and abnormal dentin structure. Mutant tooth germs formed multiple dental epithelial buds into the mesenchyme. In Epfn-/-molars, rapid ...
2007 JUL 24 ... "Patterning the size and number of tooth and its cusps," is the subject of a report. "Mice and rats, two species of rodents, show some dental similarities such as tooth number and ... were investigated by the heterospecific recombinations of tissues from the molar tooth germs of mice and rats," researchers in Seoul, South Korea report.
"Our ...
2008 MAR 4 ... D. However, the amount of CB28k expression in the kidneys of vitamin D receptor-null mice was reported to be similar to that in wild type mice, suggesting no dependence on ... various doses, quantitative RT-PCR analyses of CB9k and CB28k mRNA were performed using toothgerms from the lower first molars of ICR mice. CB9k-immunoreactivity was detected ...
2007 JUN 26 ... in "Diverse effects of c-src deficiency on molar tooth development and eruption in mice" have been presented. According to a study from Tokyo, Japan, "C-src deficiency is ... From early development, the alveolar space was much narrower in the upper molar tooth germs than in the lower ones in both wild type and homozygous animals, and particularly so in ...
2007 JUN 5 ... "Patterning the size and number of tooth and its cusps," is the subject of a report. "Mice and rats, two species of rodents, show some dental similarities such as tooth number and ... were investigated by the heterospecific recombinations of tissues from the molar tooth germs of mice and rats," researchers in Seoul, South Korea report.
"Our ...
2008 MAR 3 ... mutation causes overexpression of FGF23 in teeth,' new data in life sciences. "Hyp mice have a disorder in phosphate homeostasis, and display hypo-mineralization in bones and ... teeth of WT mice. Quantitative RT-PCR analyses for FGF23 were performed using the toothgerms of WT and Hyp mice in both in vivo and in vitro experiments. Undifferentiated and ...
2007 JUN 4 ... scaffold.
"Heterogeneous cells dissociated from embryonic day 14 (E14) mice tooth germs were seeded on a scaffold and implanted under a kidney capsule in adult mice. The ...
2008 OCT 28 ... and function of Dlx genes during amelogenesis. Analysis of Dlx2/LacZ transgenic reporter mice, Dlx2 and Dlxl/Dlx2 null mutant mice, identified spatial variations in Dlx2 expression ... "Tooth development is a complex process including successive stages of initiation, ... null mutant mice, identified spatial variations in Dlx2 expression within molar tooth germs and suggests a role for Dlx2 in the organization of preameloblastic cells as a palisade ...
2007 SEP 18 ... and dentin formation during tooth morphogenesis. Towards this end, we generated mice with conditional inactivation of the Tgfbr2 gene in cranial neural crest derived cells. ... mutant mice at E18.5. Following kidney capsule transplantation, Tgfbr2 mutant tooth germs expressed a reduced level of Co11a1 and Dspp and exhibited defects including decreased ...
2007 JUL 2 ... polytetrafluoroethylene membrane and were transplanted subcutaneously into 11 nude mice. The animals were sacrificed after 3 and 8 weeks, and the new specimens were processed ... differentiation into cementoblasts. In this study, EMPs were extracted from porcine toothgerms by the use of acetic acid. BMSCs obtained from porcine iliac marrow aspiration ...
2007 MAY 22 ... scaffold.
"Heterogeneous cells dissociated from embryonic day 14 (E14) mice tooth germs were seeded on a scaffold and implanted under a kidney capsule in adult mice. The ...
2007 APR 23 ... scaffold.
"Heterogeneous cells dissociated from embryonic day 14 (E14) mice tooth germs were seeded on a scaffold and implanted under a kidney capsule in adult mice. The ...
2007 JUL 10 ... "The primary enamel knot determines the position of the first buccal cusp in developing mice molars. The enamel knot (EK), which is located in the center of bud and cap stage tooth ... molars. The enamel knot (EK), which is located in the center of bud and cap stage tooth germs, is a transitory cluster of non-dividing epithelial cells. The EK acts as a signaling ...
2007 JUL 17 ... scaffold.
"Heterogeneous cells dissociated from embryonic day 14 (E14) mice tooth germs were seeded on a scaffold and implanted under a kidney capsule in adult mice. The ...
2007 JUL 24 ... scaffold.
"Heterogeneous cells dissociated from embryonic day 14 (E14) mice tooth germs were seeded on a scaffold and implanted under a kidney capsule in adult mice. The ...
2007 AUG 21 ... scaffold.
"Heterogeneous cells dissociated from embryonic day 14 (E14) mice tooth germs were seeded on a scaffold and implanted under a kidney capsule in adult mice. The ...
2007 JUL 16 ... "Patterning the size and number of tooth and its cusps," is the subject of a report. "Mice and rats, two species of rodents, show some dental similarities such as tooth number and ... were investigated by the heterospecific recombinations of tissues from the molar tooth germs of mice and rats," researchers in Seoul, South Korea report.
"Our ...
