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2009 NOV 28 ... the treatment of hemophilia. GTC is also developing a portfolio of follow-on biologic monoclonal antibodies and a CD20 antibody with enhanced ADCC (antibody-dependent cell-mediated ...
2009 NOV 24 ... responses of peripheral blood mononuclear cells after stimulation with anti-CD3 monoclonal antibody. Results show that the proportion of naive CD8(+) T lymphocytes was reduced by 32% ...
2009 NOV 24 ... enzyme-linked immunosorbent assay (DC-ELISA) based on a cadmium-chelate-specific monoclonal antibody has been developed. The DC-ELISA showed an IC50 of 2.30 mu g/L with a detection limit of ...
2009 NOV 24 ... from 40 cases of tuberculous lymphadenitis was evaluated by immunohistochemistry using a monoclonal antibody (MIB-1) to Ki-67. The PI was defined as the percentage of AMs with positive nuclear ...
2009 NOV 24 ... in the range of 37-92 kDa. The 70 kDa adhesin was also recognized by a protective monoclonal antibody raised against a gp70 antigen of S. schenckii (mAb P6E7). Confocal microscopy confirmed ...
2009 NOV 23 ... Drug Development, Drug Resistance, Drug Therapy, Drugs, Herceptin, Medical Device, Monoclonal Antibodies, Oncology, Pharmaceuticals, Recurrence, Therapy, Trastuzumab, Treatment, ... growth factor receptor, < 35% are responsive to treatment with the HER2-disabling antibody, called trastuzumab (Herceptin)." "Despite those statistics, women ...
2009 NOV 23 ... agent for early detection of atherosclerotic plaques. Covalent attachment of anti-ICAM-1 monoclonal antibodies to pre-formed liposomes stabilized with polyethylene glycol yielded ILs, with ... Danila and colleagues published their study in Texas Heart Institute Journal (Antibody-Labeled Liposomes for CT Imaging of Atherosclerotic Plaques In Vitro Investigation of an ...
2009 NOV 23 ... on the specific cell type utilized in the assay. Using Fc gamma receptor blocking monoclonal antibodies, we found that at least three murine Fc gamma receptor classes, IIB, III, and ... "Anthrax toxin neutralization assays are used to measure functional antibody levels elicited by anthrax vaccines in both preclinical and clinical studies. In this ...
2009 NOV 23 ... substitutions that decreased cellular receptor binding avidity. Analyzing a panel of monoclonal antibody hemagglutinin escape mutants revealed a positive correlation between receptor binding ...
2009 NOV 29 ... Disorder, Biotechnology, Eye Disease, Immunology, Inflammation, Medical Device, Monoclonal Antibodies, Ophthalmology, Surgery, University of Michigan Health ... non-Hodgkin's B-cell lymphoma. The drug works by depleting B cells-the body's normal antibody-producing cells-that appear to go awry in autoimmune diseases.Collaborating ...
2009 NOV 23 ... Drugs, FDA, Gastroenterology, Gastrointestinal, Inflammatory Bowel Disease, Infliximab, Monoclonal Antibodies, Necrosis, Pharmaceuticals, Therapy, Treatment, U.S. Food and Drug ... with inflammatory bowel disease (IBD) exceed 1.7 billion dollars/year. Infliximab, an antibody to tumor necrosis factor-alpha, has been extensively used to treat IBD, with 390,000 IBD ...
2009 NOV 23 ... global collaboration to discover, develop, and commercialize fully-human therapeutic monoclonal antibodies. Sanofi-aventis will increase its annual funding commitment from ... will contribute to the collaboration its next generation technologies related to antibody generation. Sanofi-aventis has an option to extend the discovery program ...
2009 NOV 28 -- According to a study from Rome, Italy, "Bronchiolitis is a distressing, potentially life-threatening respiratory condition that affects infants. We evaluated the incidence and risk factors of hospitalization for broncholitis in preterm infants......
2009 NOV 23 ... Histologic evaluation of articular cartilage included staining with lubricin-specific monoclonal antibody 9G3 and Safranin O. The percentage of lubricin staining on the surface of articular ...
2009 NOV 23 ... of IVIG is essentially mediated by Fab glycosylation. Moreover, experiments with a monoclonal antibody from a human cell line and IVIG Fc fragments indicated that at least two sialic acids in ...
2009 NOV 23 ... decreased survival compared to women with HER2-negative breast cancer. Trastuzumab is a monoclonal antibody that inhibits HER2 activity, making this compound an important therapeutic option for ...
