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2009 NOV 2 ... of harnessing these strains to present antigens from heterologous pathogens to the mucosal immune system shows great promise." "To fully realize this possibility, ... of these expression plasmids meet two critical criteria for V. cholerae live vector vaccine studies. First, the plasmids are highly stable in the V. cholerae vaccine strain CVD ...
2009 NOV 1 ... resemblance of nasal lymph nodes, the principal antigen uptake site of respiratory mucosal immunity, between pig and human." "Intranasal instillation of HA vaccine ...
2009 NOV 23 ... published their study in American Journal of Respiratory Cell and Molecular Biology (Mucosal Vaccine Using CTL Epitope-Pulsed Dendritic Cell Confers Protection for Intracellular Pathogen. ...
2009 NOV 2 ... later encounters a circulating H1N1 virus. In response to the vaccine, the body develops mucosal immunoglobulin A (IgA), serum immunoglobulin G (IgG), and cellular immunity to help ...
2009 NOV 17 ... "We also evaluated the kinetics of T-lymphocyte activation in both the systemic and the mucosal compartments after rAd5 administration in monkeys with preexisting immunity to Ad5. The ... The researchers concluded: "These findings indicate that the administration of a vaccine vector such as Ad5 can induce a global activation of T cells." Sun and ...
2009 NOV 1 ... over the research period to support efforts aimed at developing nanoemulsion-based mucosal vaccine adjuvants for a wide variety of antigens. "NanoBio's nanoemulsion-based ...
2009 NOV 1 ... We also observed a rapid and irreversible loss of CD4(+) T cells at multiple mucosal sites, resulting in a marked decrease of CD4:CD8 T cell ratios 0.5-4 weeks after ... immunodeficiency viruses (SHIV), although the latter have been widely used in HIV vaccine studies," scientists in the United States report. "Here, we report the ...
2009 NOV 16 ... 10(8) copies/ml; set-point values were 10(4) to 10(5) SIV RNA copies/ml. Levels of acute mucosal CD4(+) T-cell depletion were similar for treated and nontreated animals. SIVagm ... For additional information, contact I. Pandrea, University of Pittsburgh, Center Vaccine Research, 9045 Biomedial Science Tower 3, 3501 5th Avenue, Pittsburgh, PA 15261, USA. ...
2009 NOV 23 ... persistent infections in immunocompetent mice. The intranasal vaccination induced mucosal immunity effective enough to protect mice from the virus challenge via the same route. ... from lymphocytic choriomeningitis virus (LCMV) and evaluated its potency as an antiviral vaccine. The intramuscular immunization of mice with the peptide-liposome conjugates along with ...
2009 NOV 16 ... and colleagues published the results of their research in the Journal of Virology (Mucosal Innate and Adaptive Immune Responses against Herpes Simplex Virus Type 2 in a Humanized ... worldwide and a risk factor for acquiring human immunodeficiency virus. Although many vaccine candidates have shown promising results in animal models, they have failed to be ...
2009 NOV 1 ... responsible for celiac disease and helped separate maldigestion (cystic fibrosis) and mucosal malabsorption. The first comprehensive textbook of Paediatric Gastroenterology was ... Hepatology, Immunization, Pediatric Gastroenterology, Pediatrics, Pulmonology, Rotavirus Vaccine, Small-bowel Disease, Surgery, Therapy, Treatment, Vaccination. This ...
2009 NOV 1 ... responsible for celiac disease and helped separate maldigestion (cystic fibrosis) and mucosal malabsorption. The first comprehensive textbook of Paediatric Gastroenterology was ... Hepatology, Immunization, Pediatric Gastroenterology, Pediatrics, Pulmonology, Rotavirus Vaccine, Small-bowel Disease, Surgery, Therapy, Treatment, Vaccination. This ...
2009 NOV 2 ... by enzyme-linked immunosorbent assay 35 days after immunization. Also, serum IgA and mucosal (feces) IgA antibodies were detected in 30% of the mice immunized with Cp23. In ... to a study from the United States, "Attenuated Salmonella enterica serovar Typhimurium vaccine strain SL3261 was used as an antigen delivery system for the oral immunization of mice ...
2009 NOV 1 ... splenic IFN-gamma recall responses, as well as the production of systemic and mucosal antibodies. Intranasal vaccination with KKF235 protected mice from subsequent homotypic ... According to recent research published in the journal Vaccine, "Francisella tularensis, an intracellular Gram-negative bacterium, is the causative ...
