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2009 NOV 23 ... however." "We investigated the importance of conjunctival mast cells in a murine model of IgE-mediated allergic conjunctivitis. IgE-mediated allergic conjunctivitis was ...
2009 NOV 23 ... the cell adhesion mediated by the CX3CL1-CX3CR1 axis. Finally, in a noninfectious murine model of peritonitis, F1 strongly inhibited macrophage accumulation. These data reveal a ...
2009 NOV 23 ... diseases." "We sought to determine the effects of APN deficiency in a murine model of chronic asthma. Allergic airway inflammation was induced in APN-deficient mice ...
2009 NOV 23 ... frequency, insulitis, and/or beta-cell area. Here, we show that combination therapy of murine ATG and GCSF was remarkably effective at reversing new-onset diabetes in NOD mice and ... factor (GCSF), to reverse overt hyperglycemia in the nonobese diabetic (NOD) mouse model of type 1 diabetes. Effects of each therapy were tested in pre-diabetic and diabetic ...
2009 NOV 23 ... receptors, with a proposed role in inflammatory cell recruitment. Neutralization of murine CD97 with the anti-mCD97 mAb 1B2 was efficacious in prevention of murine ... anti-mCD97 mAb 1B2 was efficacious in prevention of murine collagen-induced arthritis, a model with features resembling rheumatoid arthritis," researchers in Oss, Netherlands report. ...
2009 NOV 23 ... Tim-3/galectin-9 pathway in an allogeneic heart transplant model." "The murine cardiac transplant model from BALB/c (H-2d) to C57BL/6 (H-2b) was built. The recipients ...
2009 NOV 24 ... from Brazil, "The virulence of four Sporothrix schenckii isolates was compared in a murine model of sporotrichosis, together with the protein pattern of the yeast cell surface and the ...
2009 NOV 23 ... We observed a profound disorder in myofiber size and structural organization in a murine model expressing the Bin1 SH3 region. In addition, satellite cell-derived myogenesis was ...
2009 NOV 23 ... in vivo tissue formation is still lacking. Here, we describe the unique capacity of the murine bone marrow-derived D1 MSC cell line, which differentiates in vitro into at least three ... that direct and control in vitro osteogenic differentiation of MSCs, a rapid and simple model to evaluate in vivo tissue formation is still lacking. Here, we describe the unique ...
2009 NOV 23 ... The researchers concluded: "Our data indicate that CD39 deficiency exacerbates murine colitis and suggest that CD39 polymorphisms are associated with inflammatory bowel ... inflammatory bowel disease." "We studied these possibilities in a mouse model of colitis using mice with global CD39 deletion. We then tested whether human genetic ...
2009 NOV 23 ... (CHM-1) on cell viability, cell cycle arrest and apoptosis in CT-26 murine colorectal adenocarcinoma cells. For determining cell viability, the MTT assay was ... effects of CHM-1-P were evaluated in BALB/c mice inoculated with CT-26 cells orthotopic model. CHM-1 induced CT-26 cell viability inhibition and morphologic changes in a ...
2009 NOV 23 ... the Journal of Immunotherapy (Local AdCD40L Gene Therapy is Effective for Disseminated Murine Experimental Cancer by Breaking T-cell Tolerance and Inducing Tumor Cell Growth ... CD40L gene transfer through adenoviral vectors (AdCD40L) was used to treat an aggressive model of disseminated bladder cancer (MB49/ C57BL/6). Three weekly AdCD40L vector ...
2009 NOV 23 ... an IC50 of 349 nM in the human blood LTB4 inhibition assay, and is efficacious in a murine ovalbumin model of allergen-induced asthma," wrote J.H. Hutchinson and colleagues. ...
2009 NOV 23 ... (HS) chains, on the inflammatory response associated with allergic inflammation in a murine model of OVA-induced acute airway inflammation was investigated. OVA-exposed ...
2009 NOV 23 ... 708a. Despite missing several putative virulence genes, 708a was fully virulent in a murine melioidosis model," wrote L.A. Trunck and colleagues, Colorado State University. ...
2009 NOV 23 ... (Aerosol Delivery of Liposomal Formulated Paclitaxel and Vitamin E Analog Reduces Murine Mammary Tumor Burden and Metastases. Experimental Biology and Medicine, ... paclitaxel and alpha-TEA was tested in the BALB/c syngeneic 66cl-4-GFP mammary cancer model." "Both agents were formulated into liposomes and delivered by inhalation ...
2009 NOV 23 ... occur independently of glucose lowering." "By using a hindlimb ischemia murine model, in this study we have found that pioglitazone restores the blood flow recovery and ...
2009 NOV 23 ... the absence of IL-4 and IL-13 on the T(H)17 response to epicutaneous sensitization in a murine model of allergic skin inflammation with features of AD. Wild-type, IL4 knockout (KO), IL13 KO ...
2009 NOV 23 ... on several human tumor cell lines and on the subcutaneously grafted experimental L1210 murine tumor in mice. SQgem nanomedicine displayed an efficient cytotoxicity against a variety ... higher anticancer activity compared with gemcitabine in an intravenously grafted tumor model in mice. To further establish the candidature of this nanomedicine for clinical trials, ...